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“Mesenchymal Stem Cells – Advances & Applications” — Market Size, Segments, Trends, & Projections through 2020

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Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, and potentially other cell types. For years, it has been clear that MSCs are a leading type of stem cell being investigated for therapeutic applications, because they have the potential to treat a wide range of acute and degenerative diseases.

In addition to secreting factors that can stimulate tissue repair, MSCs can substantially alter their microenvironment, exerting effects that are both anti-inflammatory and anti-fibrotic. MSCs are also advantageous over other stem cells types, because they avoid the ethical issues that surround embryonic stem cell research and appear to be immuno-privileged.

Importantly, MSCs also well-suited for use in the exponential growth area of 3D printing, because of their unusual capacity to form structural tissues. [Read more…]

Capitalizing on Mesenchymal Stem Cell Applications – Market Size, Segments, & Trends

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Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, beta-pancreatic islets cells, and potentially, other cell types. MSCs are of intense therapeutic interest because they represent a population of cells with the potential to treat a wide range of acute and degenerative diseases.

MSCs are advantageous over other stem cells types for a variety of reasons: they avoid the ethical issues that surround embryonic stem cell research, and repeated studies have found MSCs to be immuno-privileged, which make them an advantageous cell type for allogenic transplantation. MSCs reduce both the risks of rejection and complications of transplantation. Recently, there have been advances in the use of autologous mesenchymal stem cells to regenerate human tissues, including cartilage, meniscus, tendons, bone fractures, and more. [Read more…]

Do You Know Opportunities for Commercializing Stem Cells, by Stem Cell Type?

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Commonly investigated stem cell types include embryonic stem cells (ESCs), as well as adult stem cell types that include mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs), neural stem cells (NSCs), and induced pluripotent stem cells (iPSCs). There are also other less common stem cell types, including dental pulp stem cells (DPSCs), adipose-derived stem cells (ADSCs), and a variety of perinatal stem cell types, including amniotic stem cells, placental stem cells, umbilical cord blood stem cells, and cord tissue stem cells.

Cancer stem cells also exist, giving rise to clonal populations of cells that form tumors or disperse within the body. Each of these stem cell types represents unique opportunities for research product development.

Importantly, literature concerning the biology, characteristics, and applications of stem cells has flourished over the past few decades.

In full-year 2015, there were 25,613 stem cell scientific publications released, and an all-time search returns 259,218 stem cell scientific publications (Pubmed.gov). [Read more…]

Launching June 2016 – Strategic Development of Neural Stem and Progenitor Cell Products

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Neurogenesis is the process by which neurons are created. This process is most active during pre-natal development when neurogenesis is responsible for populating the growing brain.

Neural stem cells (NSCs) are the self-renewing, multipotent cells that differentiate into the main phenotypes of the nervous system. These cell types include neurons, astrocytes, and oligodendrocytes. Neural progenitor cells (NPCs) are the progeny of stem cell division that normally undergo a limited number of replication cycles in vivo.
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Day 1 Recap for the “Biorepositories and Sample Management Summit”

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Biobanks are biomedical research facilities that process and stores a wide variety of biospecimens, to include whole tissue, blood, DNA, plasma, purified saliva, cell lines, stem cell populations, and more. The goal of biobanking is to preserve biological samples for storage, and importantly, potential use at a later point in time. Biobanks are now playing a major role in assisting pharmaceutical companies with drug discovery and development efforts. They are also driving forward precision medicine efforts, as they have the capacity to allow physicians to select the best treatment option for specific patients. However, effectively preserving tens of thousands, or even hundreds of thousands, of biological samples can be a daunting task.

To honor this growing industry, speakers at the “Biorepositories and Sample Management Summit” held today at the Hilton Hotel in Boston, Massachusetts delivered a jam-packed day of content.

We heard presenters discuss biobanking topics that included: [Read more…]

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