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Hematopoietic Stem Cells (HSCs)

The Future of Stem Cell Therapeutics – Balancing Safety and Efficacy

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What do we know of the safety and efficacy of stem cell therapeutics? Over 50 years have passed since the discovery of hematopoietic stem cells (bone marrow transplantation to cure diseases such as leukemia), over 20 years since the discovery of human embryonic stem cells (hESC), and 15 years since the discovery of induced pluripotent stem cells (iPS cells). There are now thousands of stem cell trials underway in clinics worldwide.

Despite this experience, what do we actually know about the safety and efficacy of stem cell therapeutics? [Read more…]

The French Blood Agency announces agreement with TreeFrog Therapeutics to scale-up manufacturing of iPS-derived hematopoietic stem cell transplants

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TreeFrog Therapeutics will apply its proprietary technology for the mass-production of stem cell therapies to the world-first single-step protocol allowing the differentiation of human induced pluripotent stem cells (iPSCs) into fully functional human hematopoietic stem cells (HSCs). Resulting off-the-shelf universal HSC grafts could reduce costs and waiting times for patients in need of a bone marrow transplant.

Bordeaux, France – November, 17th, 2020 —The French Blood Agency (EFS) and TreeFrog Therapeutics announce a partnership to advance the mass-production of iPSC-derived HSC transplants based on a patented differentiation protocol developed by the EFS (UMR S938), the Institute for Radioprotection and Nuclear Safety (IRSN) and Sorbonne University[1]. [Read more…]

Do You Know The 5 Types Of Stem Cells?

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As you start to learn about stem cells, one of the most common questions to have is, “What types of stem cells exist?” There is not an agreed-upon number of stem cell types, because one can classify stem cells either by differentiation potential (what they can turn into) or by origin (from where they are sourced). This post is dedicated to explaining the five types of stem cells, based on differentiation potential. [Read more…]

Stem Cell Transplants: What To Know About This Life-Saving Procedure

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Stem cell transplants are a medical procedure in which which stem cells are transplanted into an injured or diseased recipient. This procedure can either involve stem cells derived from one’s self or stem cells  derived from a healthy donor.

In this article:

  1. Types of Stem Cell Transplant in Treating Diseases
  2. Advantages of Stem Cell Transplant in Treating Diseases
  3. Stem Cell Collection
  4. Stem Cell Transplant Procedure
  5. Stem Cell Transplant Recovery
  6. Diseases Treated with Stem Cell Transplant
  7. Stem Cell Transplant Success Rate

[Read more…]

Who Is CryoHoldco? Latin America’s Largest Cord Blood Bank

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CryoHoldco is a stem cell bank holding company that is the market leader in Latin America and one of the top 10 largest cord blood banks in the world. By the end of 2020, CryoHoldco will be seven times larger than any other stem cell bank in Latin America and will have 275,000 stem cell units in storage.

[Read more…]

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