CAR-T Market Report, 321 Pages
Published May 2023
CAR-T cell therapy is a remarkably promising treatment for cancer patients. It is a type of immunotherapy where doctors collect immune cells, modify them in a laboratory, and provide them the power to easily recognize and kill cancer cells. When infused into a patient, the cells get multiplied and stay in the body as “living drugs.”
T-cells form the backbone of CAR-T cell therapy. T-cells are the workhorses of our immune system and play a key role in directing the immune response and killing cells infected by pathogens. In CAR-T cell therapy, blood is drawn from the patient and the T-cells are separated out. In the laboratory, a disarmed virus is then used to genetically engineer the T-cells to produce chimeric antigen receptors (CARs) on their surface. Once infused into the patient, these CARs enable the T-cells to recognize and attach to an antigen on the cancer cell, leading to its destruction.
CAR-T Cell Therapy Market
Scientific progress within the field of cancer immunotherapy has led to six CAR-T cell therapy approvals by the U.S. FDA, including:
- Kymriah (tisagenlecleucel)
- Yescarta (axicabtagene ciloleucel)
- Tecartus (brexucabtagene autoleucel)
- Breyanzi (lisocabtagene maraleucel)
- Abecma (idecabtagene vicleucel)
- Carvykti (Ciltacabtagene autoleucel)
In addition, Relma-cel’s (Relmacabtagene) received approval from the NMPA in China.
Unfortunately, the blood cancers treatable by the currently approved CAR-T cell therapies represent less than 5% of cancer patients worldwide. At present, there are over 1,100 ongoing CAR-T clinical trials focusing on solutions to other types of blood cancers and solid tumors, which represent the other 95% of cancer cases. This growth in the number of clinical trials has been fueled by the unprecedented 90% remission rate shown by most of the approved CAR-T therapies.
These historic approvals demonstrate that the CAR-T market has arrived and is taking the biotech industry by storm. This has driven CAR-T funding to staggering new heights. At first the trend was subtle, but the tide has swelled as CAR-T start-ups have been richly funded by investors eager to get into this rapidly expanding area of regenerative medicine.
Additionally, there has been over $100 billion of market capitalization from CAR-T companies in recent years. Financing rounds by CAR-T companies have approached $4 billion, while CAR-T industry partnerships have contributed an astounding $2 billion. M&A activity has been even more aggressive, with Celgene snagging Juno Therapeutics for $9 billion and Bristol-Myers Squibb (BMS) acquiring Celgene for $74B. Gilead’s acquisition of Kite Pharma for $11.9 billion also made waves, as did other transactions, such as Astellas Pharma’s acquisition of Xyphos Biosciences and its CAR-T technology for $665 million.
This billion dollar market would not have been possible without the remarkable efficacy of the early CAR-T therapies in treating several types of blood cancers. Ranging from small start-ups to billion-dollar companies, CAR-T companies are proliferating in all healthcare markets worldwide.
Recently released, this 321-page report reveals:
- CAR-T market size determinations with segmentation by product, geography, and indication, as well as future forecasts through 2028
- Detailed coverage of the approved CAR-T products, including regulatory approvals, pricing, reimbursement, and market penetration
- Clinical trial activity by type, geography, phase and sponsor
- Comprehensive CAR-T patent analysis, including top inventors, patent holders, patent types, geographies, and most cited patents
- CAR-T industry mergers and acquisitions, IPOs, and financing events
- Deal-making, strategic partnerships, and co-commercialization agreements within the CAR-T sector
- Little known market trends, future directions, and emerging opportunities
- Profiles of leading CAR-T competitors composing the global marketplace
- And so much more
This global strategic report will position you to:
- Capitalize on rapidly emerging trends
- Optimize decision-making
- Reduce company risk
- Approach partners/investors for collaboration or funding
- Implement an informed and advantageous business strategy in 2023
Although progressing at breakneck speed, developments within the field of CAR-T cell therapy are still early stage, positioning the market for remarkable expansion. Today is similar to the launch of the first chemotherapy treatments, when oncologists started treating patients with a single type of chemotherapy. Now, fifty years later, cancer patients are treated with over a hundred different chemotherapy agents. In the same way, we will soon have numerous CAR-T therapies available to treat liquid cancers, solid tumors, and autoimmune diseases, as well as inflammatory conditions.
TABLE OF CONTENTS: Global CAR-T Cell Therapy Market – Market Size, Forecasts, Trials & Trends, 2023
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The content within this report was compiled using a diverse range of sources, as described in this Research Methodology.
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