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Stem Cell Treatments For COPD in 2022

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A diagnosis of chronic obstructive pulmonary disease (COPD) can be alarming, but thanks to stem cell treatments for COPD, the situation may not be dire. Once a patient develops COPD, it means that he or she has developed complications to existing breathing problems. The chronic disease happens when inflammation in the lung interferes with airflow.

Not being able to breathe properly and having frequent chest tightness can be distressing, especially when it is caused by a chronic disease, rather than a temporary illness like bronchitis. Thankfully, new options for treatment emerge every day. Among these options are stem cell treatments for COPD. [Read more…]

denovoMATRIX Launches Novel Microcarrier to Advance Cell and Gene Therapy Manufacturing

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DRESDEN, Germany, May. 04, 2022 — denovoMATRIX GmbH, an innovator in cell and gene therapy (CGT) manufacturing, announced the launch of a novel microcarrier for increasing access to high-quality mesenchymal stromal cells (MSCs) for stem cell-based therapies. The product, termed beadMATRIX, is designed to enable MSC proliferation and harvest in xeno-/serum-free media with high efficiency and stemness.

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How Human iPSCs are Revolutionizing Drug Discovery in 2022

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Drug discovery involves high cost and uncertain outcomes.  Only a few companies can take the risk of investing enormous amounts of money into research and testing, only to see undesirable side effects emerge during the final human clinical trials. In many cases, companies are spending millions of dollars to fail during clinical testing.

Now, some new medicines are being tested for safety on specialized cells developed from human pluripotent cell lines. Cell types which are frequently being using within drug discovery applications include heart (cardiomyocytes) and liver cells (hepatocytes), which are the organs where 80% of drug failures occur. [Read more…]

Cell Therapy Manufacturing | Factors Driving Interest in Cell Therapy CDMOs

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Cell therapy manufacturing is becoming of growing importance as more and more cell therapeutics make their way through clinical trials. One of the major issues with moving cell therapy products from “bench to bedside” has been manufacturing bottlenecks. The heterogeneous nature of cell therapy products has introduced manufacturing complexity and regulatory concerns, as well as scale-up complexities that are not present within traditional pharmaceutical manufacturing.

Cell Therapy Manufacturing CDMOs

While these realities may sound like negative factors for the industry, the reality is quite the opposite. For cell therapy CDMOs, these factors create pressures for cell therapy companies to seek third-party partners who possess technical, manufacturing, and regulatory expertise in cell therapy development and manufacturing. [Read more…]

Can We Extend the Human Lifespan With Regenerative Medicine?

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Regenerative medicine is a fascinating topic, because it requires you to ask yourself: Would you want to live to be 200 years old? A scientist from Stanford University thinks that it’s possible – so much so that he has placed a bet that there is someone alive today who will live to be 200 years old.

Over recent decades, modern scientific developments have led to a dramatic increase in human lifespan. But how much further can we go? Does regenerative medicine have the power to enable us all to live for many more years?

Let’s dive into this fascinating topic and find out more about regenerative medicine. How could it extend human life into the future? [Read more…]

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