Biotech founder and CEO Jan Jensen has never been one for following the beaten track. As a young scientist studying the formation of insulin-producing pancreatic cells, Jensen questioned the prevailing view that these cells descended from neuroectoderm. His pancreatic embryonic tissue studies told him otherwise: insulin-producing pancreatic cells originate from within the pancreas itself. Jensen’s hypothesis, now the accepted view, and his further studies made him the first developmental biologist at Novo Nordisk, at a time when the world’s largest insulin producer had little interest in cell-based therapy. Now, 20 years later, Novo Nordisk is at the forefront of cell-based Type I Diabetes research. [Read more…]
Cell Therapy Manufacturing | Factors Driving Interest in Cell Therapy CDMOs
Cell therapy manufacturing is becoming of growing importance as more and more cell therapeutics make their way through clinical trials. One of the major issues with moving cell therapy products from “bench to bedside” has been manufacturing bottlenecks. The heterogeneous nature of cell therapy products has introduced manufacturing complexity and regulatory concerns, as well as scale-up complexities that are not present within traditional pharmaceutical manufacturing.
Cell Therapy Manufacturing CDMOs
While these realities may sound like negative factors for the industry, the reality is quite the opposite. For cell therapy CDMOs, these factors create pressures for cell therapy companies to seek third-party partners who possess technical, manufacturing, and regulatory expertise in cell therapy development and manufacturing. [Read more…]
Pivotal Trends Impacting the Global Cord Blood Industry in 2023
The cord blood industry came into existence in the early 1990’s with the formation of several cord blood banks in the U.S. and worldwide. It has been 40 years since it was first proposed that stem and progenitor cells were present in human cord blood. [Read more…]
Who Discovered Stem Cells? The Answers Revealed
Who discovered stem cells is a question worthy of exploration. While Robert Hooke first discovered the concept of cells themselves, the discovery of stem cells is usually credited to Drs. James Till & Ernset McCulloch.
For several hundred years, researchers have known that the human body is comprised of trillions of tiny structures. Known as cells, these structures can only be seen at a microscopic level. These cells come in hundreds of variations – 200, to be exact – and serve multitudinous functions within the human body. These functions include pumping blood, digesting food, and ridding our bodies of toxins and waste products, among others. [Read more…]
The Pipeline for iPSC-Derived Cell Therapeutics in 2023
Despite progress involving the use of induced pluripotent stem cells (iPSCs) within disease modeling and drug discovery applications, it will be a long path to achieve the broad-scale use of iPSC-derived cell types in human patients. [Read more…]
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