Mogrify (Cell Mogrify Ltd) is a private biotechnology company has developed a direct cellular conversion technology to allow for the transformation (transmogrification) of any mature human cell type into any other – without going through a pluripotent stem cell- or progenitor cell-state. [Read more…]
Analysis of Induced Pluripotent Stem Cell (iPSC) Patents
The landscape for induced pluripotent stem cell (iPSC or iPS cell) patents has changed substantially over the past 10 years, evolving to be geographically clustered in four specific regions.
As background, groundbreaking experimentation led to the discovery of iPSCs in 2006, which are adult cells that are transformed into embryonic-like stem cells through the manipulation of gene expression or other related methods. In 2007, follow-up experiments proved human adult cells could be transformed into iPSC cells.
Since the discovery of iPSCs, a large and thriving research product market has grown into existence, largely because the cells are completely non-controversial and can be generated directly from adult cells.
Role of Induced Pluripotent Stem Cell (iPSC) Patent Analysis
Today, the number of iPSC products sold worldwide is increasing with double-digit growth, and 22% of all stem cell researchers self-report having used iPSCs within a research project. It is clear that iPSCs represent a lucrative product market, but commercializing the cell type involves careful and due diligence, because the cells are still a relatively new discovery.
Because the iPSC industry is a rapidly-evolving area, major research findings and technical discoveries are frequently announced . Therefore, to launch iPSC products and technologies, one of the key areas that company management and investors must consider is the patent landscape for the cell type. [Read more…]
Cynata Completes Phase I Trial for CYP-001, Triggers Option Window for Fujifilm
It is official. Australian stem cell company Cynata Therapeutics has completed the world’s first Phase I trial involving an induced pluripotent stem cell (iPSC) derived therapeutic product. The landmark study involved the company’s lead product, CYP-001, an iPSC-derived mesenchymal stem cell (MSC) product that can be manufactured at therapeutic grade and at mass scale using Cynata’s Cymerus™ platform technology.
Next, the company will be initiating Phase II trials in graft-versus-host disease (GvHD), critical limb ischemia (CLI) and osteoarthritis, showcasing the power of Cynata’s platform technology to be leveraged across multiple indications. Osteoarthritis will be Cynata’s largest clinical trial to date and also one of the largest ever for an MSC product. [Read more…]
Unconventional Leukemia Treatment Options
Learn how a stem cell transplant presents a promising leukemia treatment option in this article. [Read more…]
FDA Accepts BrainStorm’s NurOwn® IND Application for Progressive Multiple Sclerosis
U.S. Phase 2 Study to Begin in First Quarter of 2019
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