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Home » Stem Cells » HSCs » Page 3

Hematopoietic Stem Cells (HSCs)

When Did Banking Cord Blood and Tissue Banking Start?

August 16, 2021 By Cade Hildreth (CEO) Leave a Comment

Banking Cord Blood | When Did Cord Blood Banking Start?

The global cord blood industry came into existence in the early 1990’s with the formation of several leading cord blood banks in the USA, followed by the establishment of cord blood banks across the globe. However, the history of cord blood stem cell transplantation begins much earlier than that. [Read more…]

Filed Under: Cord Blood, HSCs Tagged With: cord blood, cord tissue, placenta

Comparison of Top U.S. Cord Blood Banks – CBR, ViaCord, & Cryo-Cell

January 4, 2021 By Cade Hildreth (CEO) 1 Comment

cord blood banks comparison - top cord blood banks

This article is a comparison of the top 3 largest cord blood banks in the United States.

In this article:

  1. Purpose of Comparison
  2. Top 3 Largest U.S. Cord Blood Banks by Units Banked
  3. Cord Blood Bank Comparison: Top 3 U.S. Cord Blood Banks

What You Should Know About the Top Cord Blood Banks

The top three U.S. cord blood banks by the number of units stored are:

  1. Cord Blood Registry (CBR) -San Bruno, CA
  2. ViaCord – Waltham, MA
  3. Cryo-Cell International – Oldsmar, FL

The Purpose of Comparison

The standard used to identify these cord blood banks was the number of umbilical cord blood and tissue units stored by each company.

The purpose of this analysis is to compare pricing and banking services among the largest cord blood banks within the U.S., the most mature cord blood banking market in the world.

These three industry giants also represent several of the largest cord blood banks worldwide.

Top 3 Largest U.S. Cord Blood Banks by Units Banked

The three cord blood bank companies considered in this analysis are Cord Blood Registry, ViaCord, and Cryo-Cell. These three companies are not only the three market leaders in the United States by the number of cord blood and tissue units banked but are also some of the largest cord blood banks worldwide.

1. Cord Blood Registry | CBR Cord Blood Registry

The Cord Blood Registry or CBR is unique because it is currently the world’s largest cord blood bank, with over a half million cord blood and cord tissue units in storage. This is substantially more than its nearest competitor, ViaCord, which has 350,000 units stored. It was acquired by pharmaceutical giant, AMAG Pharmaceuticals, for $700 million in June 2015.

The company’s mission is “to support the advancement of newborn stem cell research, with the hope that the investment you are making now will be valuable to your family in the future.” They provide a high-quality system for the preservation of stem cells and its long-term storage. They created this system to protect the resources that can be beneficial to future medical uses of families who banked in them.

2. ViaCord Cord Blood Banking

Viacord stands out in the marketplace because it became a part of PerkinElmer, a global company with $2.2 billion dollars in annual revenue, since October of 2006. Currently, ViaCord has released the most cord blood units for medical transplant and has the highest survival rate for cord blood transplant among companies that have shared complete transplant data.

The one-year survival rate for patients who were treated with the company’s cord blood units is 88%, and the long-term patient survival rate is 82%.1

The company’s approach is simple. They apply advanced science to provide their customers a high-quality collection of stem cells and storage procedure. Aside from umbilical cord tissue and cord blood banking, they also offer genomic testing, a diagnostic DNA testing to determine any health issues or disorders before symptoms appear. This procedure also helps families make better decisions in dealing with life-threatening diseases.

3. Cryo-Cell International Cord Blood Banking

In 1989, Cryo-Cell International was founded in Oldsmar, FL, making it the oldest cord blood bank in the world. In 1992, it began to store cord blood. In addition to pursuing a wide variety of accreditations (AABB, cGMP, and ISO 1345), it was the first private cord blood bank in the U.S. to be awarded FACT accreditation.

In 2017, it initiated a $100,000 Engraftment Guarantee (previously $75,000), the highest quality guarantee of any U.S. cord blood bank. It is the only private bank in the U.S. to offer the PrepaCyte-CB cord blood banking technology, a system that leads the industry in engraftment times.

The company also offers two processing methods to their clients: the premium industry and standard, which they promise clients a return on investment. They don’t require an enrollment fee as well unless the child is born and the cord blood and cord tissue have been stored and processed. Cryo-Cell gives a referral reward of one-year free storage to existing customers who have friends or family members who will bank in them.

Cord Blood Bank Comparison | Top 3 U.S. Cord Blood Banks

Part of the reason for the dominance of these three companies in terms of the total number of units stored is that they are three of the oldest cord blood banks within the U.S., founded in 1992, 1993, and 1989, respectively. All three of these cord blood banks also support cord blood research and clinical trials, which play an important role in the success of stem cell treatment in regenerative medicine.

These companies have also been successful with their stem cell campaign and are constantly getting bigger. A comparative analysis of services and features is shown below for these top 3 U.S. market leaders.

TABLE. Comparison of Services and Features Among the Top 3 U.S. Cord Blood BanksAbout Cord Blood Banking | The Top 3 Cord Blood Banks in the U.S.

Next, a comparative analysis of pricing is shown below for these U.S. cord blood banking market.

TABLE. Cord Blood Banking Cost Comparison of the Top 3 U.S. Cord Blood Banks
Cord Blood Storage Cost | The Top 3 Cord Blood Banks in the U.S.

One common thing among the top 3 cord blood banks is that they were established more than a decade ago and have continuously grown bigger over the years. It’s not surprising they are some of the largest blood banks in the world, as they have constantly evolved in terms of technology and services.

Whichever one you choose, we hope you find the best cord blood bank for your individual needs.

If you found this blog valuable, subscribe to BioInformant’s stem cell industry updates.

1 Viacord.com. ViaCord – Complete Transplant Data. [online] Available at: http://www.viacord.com/Images/ViaCord_Transplant_260_060613_tcm117-153288.pdf
2 Cordblood.com. Cord Blood Stem Cell Banking | Cord Blood Registry | CBR. [online] Available at: http://www.cordblood.com/cord-blood-banking-cost/cord-blood-stem-cells
3 Viacord.com. How much does cord blood banking cost? | ViaCord. [online] Available at: http://www.viacord.com/pricing/cord-blood-banking/index.aspx.
4 Cryo-cell.com. Enrollment in the Cord Blood and Cord Tissue Stem Cell Service | Cryo-Cell. [online] Available at: http://www.cryo-cell.com/enroll.

Filed Under: Cord Blood, HSCs

The French Blood Agency announces agreement with TreeFrog Therapeutics to scale-up manufacturing of iPS-derived hematopoietic stem cell transplants

December 2, 2020 By Cade Hildreth (CEO) Leave a Comment

TreeFrog iPSC
TreeFrog Therapeutics will apply its proprietary technology for the mass-production of stem cell therapies to the world-first single-step protocol allowing the differentiation of human induced pluripotent stem cells (iPSCs) into fully functional human hematopoietic stem cells (HSCs). Resulting off-the-shelf universal HSC grafts could reduce costs and waiting times for patients in need of a bone marrow transplant.

Bordeaux, France – November, 17th, 2020 —The French Blood Agency (EFS) and TreeFrog Therapeutics announce a partnership to advance the mass-production of iPSC-derived HSC transplants based on a patented differentiation protocol developed by the EFS (UMR S938), the Institute for Radioprotection and Nuclear Safety (IRSN) and Sorbonne University[1]. [Read more…]

Filed Under: HSCs, iPS Cells, Press Releases, Stem Cell News Tagged With: iPS cells

Stem Cell Transplants: What To Know About This Life-Saving Procedure

October 1, 2020 By Cade Hildreth (CEO) Leave a Comment

Feature | Stem Cell Transplants: Types and Procedures

Stem cell transplants are a medical procedure in which which stem cells are transplanted into an injured or diseased recipient. This procedure can either involve stem cells derived from one’s self or stem cells  derived from a healthy donor.

In this article:

  1. Types of Stem Cell Transplant in Treating Diseases
  2. Advantages of Stem Cell Transplant in Treating Diseases
  3. Stem Cell Collection
  4. Stem Cell Transplant Procedure
  5. Stem Cell Transplant Recovery
  6. Diseases Treated with Stem Cell Transplant
  7. Stem Cell Transplant Success Rate

[Read more…]

Filed Under: HSCs, Stem Cells

Top 10 Cord Blood Banks Worldwide

September 7, 2020 By Cade Hildreth (CEO) 2 Comments

cord blood banking companies | Top 10 Cord Blood Banks Worldwide

The top cord blood banks identified below were chosen based on the impact they are making on the global cord blood industry. It is critical to be educated about these 10 companies because they set important standards and practices that affect all market participants.

Leading Cord Blood Banking Companies

In this article:

  • Global Cord Blood Banking Leaders
  • Cord Blood Registry
  • ViaCord
  • Cryo-Cell
  • China Cord Blood Corporation
  • Cryo-Save
  • New York Cord Blood Program
  • CordVida
  • Americord
  • CryoHoldco
  • Vita34

Global Cord Blood Banking Leaders

The criteria used for this analysis were the number of cord blood and cord tissue units stored, the size of the company, the age of the company, and the technological innovation possessed by the company. Together, these attributes distinguish the cord blood banks below from the rest of the marketplace.

1. Cord Blood Registry

cord blood registry | Top 10 Cord Blood Banks WorldwideLocated in San Bruno, California, USA, Cord Blood Registry (CBR) was founded in 1992 by Wendy Grant and Tom Moore. With more than 20 years of history, it is one of the oldest and most trusted cord blood banks worldwide. In addition to being the only company in the region with its own storage facility, it has also had a long-standing history of AABB accreditation.

Additionally, CBR is the largest cord blood bank in the United States and worldwide by the number of cord blood and cord tissue units stored (more than 500,000 to date).

Finally, Cord Blood Registry was acquired by pharmaceutical giant AMAG Pharmaceuticals for $700 million in June of 2015, making it a well-capitalized company.

2. ViaCord

viacord | Top 10 Cord Blood Banks WorldwideLocated in Waltham, Massachusetts, USA, ViaCord is the second largest cord blood bank in the world. ViaCord has stored more than 300,000 cord blood and cord tissue units.

ViaCord was founded in 1993 by Cynthia Fisher. ViaCord has the region’s highest percentage (90%) of successful treatments using prepared cord blood stem cells.

3. Cryo-Cell

cryo-cell | Top 10 Cord Blood Banks WorldwideLocated in Oldsmar, Florida, USA, Cryo-Cell is the third largest cord blood bank in the world. To date, Cryo-Cell has stored 240,000 cord blood and cord tissue units.

Cryo-Cell was founded in 1989 but started to store cord blood stem cells in 1992, positioning it as the world’s first cord blood bank.

It serves clients from 87 different countries and makes its services available to millions of people. Cryo-Cell uses heparin-free bags to transport cord tissues in order to provide protection from allergic reactions.

4. China Cord Blood Corporation

china cord blood corporation | Top 10 Cord Blood Banks WorldwideLocated in Daxing, Beijing, China, Cord Blood Corp is the fastest-growing cord blood bank worldwide, according to Mr. Chen Bing Chuen, the Chief Financial Officer and Director of China Cord Blood Corporation.1 

It is also the largest cord blood bank in China, controlling more than 50% of the Chinese cord blood banking market share, as determined by units stored.

Recently, the Chinese government established that it would only allow one cord blood bank in each of the Chinese provinces. The Chinese government, therefore, issues one cord blood banking license per province, and the licensed company must, therefore, function as both a public (donation-based) and private (for-profit) bank.

China Cord Blood Corporation currently holds the exclusive license for three of the regions and has partial ownership in a 4th province. All of the other companies (four total) hold only one license each.

5. Cryo-Save

cryo-save | Top 10 Cord Blood Banks WorldwideLocated in Zutphen, Netherlands, Cryo-Save is the largest cord blood bank in Europe, with more than 250,000 blood stem cells in its storage capacity. Cyro-Save was founded in 2000 and changed its name from Cyro-Cell to Cyro-Save in 2003.

Its subsidiary, Cryo-Save Arabia, was the first private cord blood bank to initiate operations in the Middle East when it launched on September 11, 2006.

Cyro-Save later launched an adipose tissue stem storage service in 2010.

6. New York Cord Blood Program

new york cord blood program | Top 10 Cord Blood Banks WorldwideLocated in New York City, the New York Cord Blood Program (NCBP) is the largest non-profit cord blood bank in the world. NCBP started its operations in 1992 under New York Blood Centre.

It has more than 60,000 blood stem cells in its storage facility and collects approximately 7,000 new units each year. NCBP is currently working to enhance this capacity to a collection of about 10,000 new units each year.

Impressively, NCBP has released more than 5,300 cord blood units to patients for use in hematopoietic stem cell transplantation (HSCT). NCBP was also the first cord blood bank to be awarded NetCord-FACT accreditation in 2003.

Impressively, NCBP also received an FDA licensure for its product, HEMACORD®, in November 2011, which was the “first time ever that the FDA has licensed a stem cell product.”

7. CordVida

cordvida | Top 10 Cord Blood Banks WorldwideLocated in São Paulo, Brazil, CordVida is the largest cord blood bank in South America. It was the first cord blood bank in Brazil to offer cord tissue storage services, a service which it launched in May 2012 through a partnership with the regenerative medicine company AuxoCell Laboratories, Inc.2

CordVida was founded in 2004, received AABB accreditation in 2008, and is today responsible for approximately half of all umbilical cord blood transplants made in Brazil using private cord blood units.3 CordVida operates its own processing and storage facility in São Paulo, Brazil.

8. Americord

americord | Top 10 Cord Blood Banks WorldwideLocated in New York City, Americord was founded in 2008. Over the past three years, the company achieved a growth rate of 2,200%, making it one of the fastest-growing cord blood banks in the world.4 

Americord has several characteristics that explain its growth rate advantage over other major competitors. These include substantially lower costs for collection and 20 years of storage (standard contract term), no cancellation fees, and a higher quality guarantee.

Currently, the top cord blood banks in the U.S. offer “quality guarantee” packages that range from $25,000 to $90,000, with Americord topping that list at $90,000. Quality guarantees ensure that if a cord blood unit is needed for medical purposes, then engraftment of it will be a success or the amount of their guarantee will be paid out toward procurement of an alternative source of stem cells or a different medical treatment.

Americord raised its guarantee from $80,000 to $90,000 in mid-2014 to further separate itself from the competition and increase its trustworthiness in the eyes of its clients.

Additionally, Americord recently launched a new cord blood processing technology called CordBlood 2.0TM.5  This technology will allow the company to harvest twice as many stem cells as with other cord blood processing technologies.

9. CryoHoldco

CryoHoldco is a stem cell bank holding company that is the market leader in Latin America and one of the largest stem cell banks in the world. CryoHoldco is about five times larger (5x) than any other stem cell bank in Latin America—with more than 125,000 cord blood samples stored. When cord tissue units are also included, it has more than 130,000 stem cell units in inventory.

CryoHoldco was created in 2015 with the purpose of forming the premier stem cell banking company in Latin America. The first asset that was acquired by CryoHoldco was Cryo-Cell Mexico, the first stem cell bank in Latin America. Since investing in Cryo-Cell Mexico in mid-2015, CryoHoldco has been active in the market and has acquired a controlling interest in a regional stem cell bank in Mexico (Q4 of 2015) and acquired Stem Medicina Regenerativa (early 2016), the largest stem cell bank in Colombia.

Today, CryoHoldco represents the largest stem cell banking operation in Latin America, with over 130,000 stored samples, two state-of-the-art lab and storage facilities in Mexico and Colombia, a growing network of 10,000+ affiliated doctors, and 100+ sales offices. CryoHoldco’s state-of-the-art storage facility in Guadalajara, Mexico, has a capacity of 300,000 samples.

Finally, CryoHoldco has a diversified revenue stream and product offering, which includes cord blood and cord tissue banking and storage of mesenchymal cells derived from dental pulp. In 2016, the company had also launched adipose tissue storage and a maternity bank.

10. Vita34

vita34 | Top 10 Cord Blood Banks WorldwideFounded in 1997 in Leipzig, Germany, Vita34 was the first private cord blood bank to be established within Europe. With nearly 20 years of expertise in cord blood banking, the company now has nearly 150,000 units in inventory, making it the clear market leader within Germany.

The company has also established an impressive global reach through the utilization of partnerships, with subsidiaries and distribution partners spread across 26 countries. While these partnerships are largely concentrated within Europe, it is also active within China, Vietnam, and South America.

As with many other market leaders, Vita34 also acquires smaller competitors, establishing a majority (75%) stake in the German cord blood bank Stellacure in 2014.

Vita34’s other distinguishing trait is its high rate of successful cord blood transplants, releasing 30+ units for therapeutic use within Europe.

About BioInformant

BioInformant is the first and only market research firm to specialize in the stem cell industry. BioInformant research has been cited by the Wall Street Journal, Xconomy, and Vogue Magazine. Serving industry leaders that include GE Healthcare, Pfizer, and Goldman Sachs, BioInformant is your global leader in stem cell industry data.

To learn more, view the “Global Cord Blood Banking Industry Report 2021.”

Footnotes

1 Chen, A. (2014). Presentation: The Commercialization of Umbilical Cord Blood Banking in China and its Operational Challenges. World Cord Blood Congress, September 17, 2014.
2   WIRE, B. (2012). AuxoCell Laboratories Licenses Umbilical Cord Tissue Stem Cell Service to Brazil’s CordVida | Business Wire. [online] Businesswire.com. Available at: http://www.businesswire.com/news/home/20120606005447/en/AuxoCell-Laboratories-Licenses-Umbilical-Cord-Tissue-Stem#.VGDHAfnF91U [Accessed 7 July. 2016].
3   Ibid.
4   Prnewswire.com, (2014). With record cord blood collections, Americord aims for Inc. 500. [online] Available at: http://www.prnewswire.com/news-releases/with-record-cord-blood-collections-americord-aims-for-inc-500-240158921.html [Accessed 4 December. 2015].
5   Process, A. (2014). Market News. [online] Research.tdameritrade.com. Available at: http://research.tdameritrade.com/grid/public/markets/news/story.asp?docKey=100-296p3339&provider=PRNewswire [Accessed 4 Nov. 2014].
6   ThePortugalNews.com, (2014). Portugal home to Europe’s second largest cord blood stem cell bank – The Portugal News. [online] Available at: http://www.theportugalnews.com/news/portugal-home-to-europes-second-largest-cord-blood-stem-cell-bank/29403 [Accessed 4 July. 2015].
7   AABB.org, (2014). AABB Accredited Cord Blood (CB) Facilities. [online] Available at: http://www.aabb.org/sa/facilities/celltherapy/Pages/CordBloodAccrFac.aspx [Accessed 11 May. 2016].

What other cord blood banking companies do you think are also global leaders? Let us know in the comments below.

Up Next: Cord Blood Banking Market Consolidation

Filed Under: Cord Blood, HSCs, Stem Cells

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