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How the Cord Blood and Tissue Market is Changing

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The global cord blood and tissue banking market is consolidating, driven by the emergence of holding companies and aggressive M&A activity. This is creating risks for cord blood market participants, as well as new opportunities.

Serious threats to the industry include:

  • Low rates of stored cord blood utilization
  • Utilization of bone marrow and peripheral blood stem cells as alternative sources of stem cells for HSCT
  • Growing prevalence of haploidentical transplantation
  • Expensive transplant procedures, ranging from $200-300K
  • Difficulty educating Obstetricians about the future value of cellular therapies
  • Low rates of market penetration
  • Low rates of cord blood awareness among expectant parents

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What is Cord Tissue Banking?

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Cord tissue banking is the processing and storage of a newborn’s umbilical cord tissue or the components contains, such as Wharton’s jelly. Wharton’s jelly is a thick, gelatinous substance present within the human umbilical cord that contains a range of important cell types, such as mesenchymal stem cells (MSCs), fibroblasts and macrophages.

In this article:

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Cord Blood Banking – Present and Future Outlook

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Cord blood banking is defined as the collection and storage of stem cells present within the umbilical cord blood of a newborn for future medical use. Umbilical cord blood is rich in a type of stem cell known as a hematopoietic stem cell (HSC). A large market for the storage of these cells has come into existence over the past 30 years, with public and private cord blood banks now present in all major healthcare markets worldwide. [Read more…]

The History of Cord Blood Transplantation

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The history of cord blood banking is fascinating, because the service did not exist on a wide-spread basis until a few decades ago. Below, we introduce key historical events that have affected cord blood and cord tissue storage and how they could impact you, your family, or your investment portfolio.
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14 Terms You Must Know to Understand Cord Blood Banking

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Since the first stem cell transplant occurred more than 50 years ago (1957), there has been a nearly exponential increase in stem cell transplants, and in late 2012, the millionth stem cell transplant occurred, a landmark event in stem cell medicine.

It is clear that the stem cells contained within cord blood banking now have the potential to improve and save lives. Since the first cord blood transplant was performed in 1988, stem cells derived from umbilical blood have been used in more than 40,000 transplants worldwide.

Cord blood stem cells have distinct advantages over other sources, including that they are young, adaptable, and pure. These traits result from cord blood stem cells being the earliest (non-controversial) stem cells that can be extracted from a living human, and therefore, they haven’t been exposed to viruses, chemicals, or pollutants in the environment that can alter cell function.

While bone marrow stem cells are the most commonly recognized type of stem cell used in transplant, cord blood stem cells are increasingly showing advantages over other stem cell sources, including reduced immune reactions (such as GvHD) and a greater flexibility for HLA-mismatched cord blood units to be used in transplant.

However, many expectant parents still do not fully understand the significance of cord blood storage or grasp the technical aspects that characterize it. This is also true of many investors who are evaluating opportunities for investing in the cord blood and tissue banking market.
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