Venture capital activity within the exosome industry has gained substantial momentum in recent years, as more as more investors pursue this promising cell-free therapeutic technology. While funding events slowed in the past year and a half due to the Covid pandemic, funding events from 2016 to 2021 were particularly robust—with companies like Evox Therapeutics, ILIAS Biologics, Codiak BioSciences, ExCoBio, Evox Therapeutics, ArunA Bio, and Capricor Therapeutics leading the charge. [Read more…]
OmniSpirant Limited and EVerZom Announce the Launch of INSPIRE; an EU Project funded under the Horizon Europe research and innovation programme to develop a ground-breaking inhaled gene therapy for the treatment of lung cancer based on extracellular vesicles
Galway, 25th November 2022 –OmniSpirant Limited and EVerZom are delighted and honoured to announce the launch of INSPIRE, a €12.8 million lung cancer project funded by Horizon Europe. In one of the largest ever grants for preclinical research in lung cancer, OmniSpirant in collaboration with our European partners spanning across biotechnology, medical devices, cancer research, academia and patient advocacy, are already actively working on the project deliverables, and recently met in Galway, Ireland for the official kick-off meeting (see the picture below taken on the 28th October 2022). [Read more…]
What is the Current State of Stem Cell Derived Exosomes?
Prior to 2007, exosomes were largely considered to be tiny “trash sacs” thrown out of living cells. Around 2007, it as discovered that exosomes carry RNAs and miRNAs, along with other molecules to regulate the expression of genes between cells. This discovery paved the way for the scientists to search for improved techniques for the exploitation of exosomes in treating diseases. [Read more…]
Brexogen’s Exosome Therapy for Atopic Dermatitis, ‘BRE-AD01’ Accepted for Phase 1 Clinical Trials by US FDA
First entry to clinical trial of exosome for atopic dermatitis and the first exosome-based therapeutics in US clinical trial among Korean companies
SEOUL, South Korea I November 2, 2022 – The US FDA granted the initiation of the phase 1 clinical trial of ‘BRE-AD01’, an exosome- based therapy for atopic dermatitis. ‘BRE-AD01’ is being developed by Brexogen with its own exosome-platform technology. It is the first phase 1 clinical trial of therapeutic exosome for atopic dermatitis in major countries. This IND clearance is very meaningful in that patients with atopic dermatitis can benefit from receiving better treatment with ‘BRE-AD01’, which is armed with multiple mode of action. [Read more…]
Approved Exosome Diagnostics: ExoDx Prostate IntelliScore & Guardant360 CDx
While solid biopsies have several limitations, including but not limited to their invasive nature, liquid biopsies can offer a promising alternative. Today, a growing number of companies are developing exosome diagnostics for the non-invasive detection and prognosis of cancer and other serious medical conditions. This approach is effective because exosomes are present in almost all body fluids and critical valuable information about the cells from which they were released. [Read more…]
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