Exosomes are small vesicles ranging from 30-100nm in size that are found in nearly all eukaryotic fluids and facilitate a range of important cellular functions. Although exosomes were discovered more than 30 years ago, it was not until recently that the scientific community began to give credit to exosomes for a range of promising traits.

In this article:

1. What are Exosomes?
2. Where are Exosomes Found?
3. Exosome Therapeutics in Regenerative Medicine
4. Exosome Market Momentum
5. Companies Commercializing Exosome Technologies

[Read more…]

Exosome research is on the rise, fueled by an increasing recognition of the central role that exosomes play in intercellular (cell-to-cell) communication and transportation. As intracellular messengers, exosomes have the potential to mediate many of the therapeutics effects commonly associated with cells, with far fewer risks.

In this article:

1. Exosome Research by Dr. Gabrielsson
2. Unicyte AG on Exosomes Therapy
3. Leading Exosome Research Journals

Exosome Research

 
For competitors within the exosome marketplace, it is vital to assess existing and future trends. One of the best tools for assessing scientific progress is to review rates of exosome research.

When exosome publications are analyzed, U.S. authors have published approximately 40% of the articles and Chinese authors take second place.[1]

When the term “exosome” is searched within scientific literature, Dr. Susanne Gabrielsson from the Karolinska Institutet in Sweden is the leading author, with 37 articles, making her one of the global authorities on exosome research.

Exosome Research by Dr. Gabrielsson

A full list of Dr. Gabrielsson’s exosome publications can be viewed at this link:

https://www.ncbi.nlm.nih.gov/pubmed/?term=Gabrielsson+S%5BAuthor%5D+AND+exosome

Unicyte AG on Exosomes Therapy

When the term “extracellular vesicles” is searched, Unicyte AG, a regenerative medicine unit of Fresenius Medical Care, takes the lead. Headquartered in Switzerland, the company has published more than 100 papers on exosomes and extracellular vesicles in combination with Prof. Giovanni Camussi. The company is also a market leader in terms of patents and translational programs.

Leading Exosome Research Journals

Interestingly, two scientific journals have been particularly favorable toward exosome publications, publishing the greatest quantity to date:

• PLoS ONE – PloS ONE, a peer-reviewed open access scientific journal published by the Public Library of Science, has published 252 articles with the term “exosome” or “exosomes” in the title. A full list of the articles can be viewed here:[2] https://www.ncbi.nlm.nih.gov/pubmed/?term=%22PLoS+ONE%22+AND+exosome
• Journal of Biological Chemistry – The Journal of Biological Chemistry, a weekly peer-reviewed scientific journal published by the American Society for Biochemistry and Molecular Biology, has published 132 articles with the term “exosome” or “exosomes” in the title. A full list of the articles can be viewed here:[3] https://www.ncbi.nlm.nih.gov/pubmed/?term=%22J+Biol+Chem%22+AND+exosome

Google Trend data also shows a clear linear increase in interest in exosome-related topics. To compete for dominance within this market, it is essential to identify trends as they begin to impact the marketplace, not after they are in full effect.

To learn more, view the “Market for Stem Cell Exosomes.”

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In your opinion how will the research into exosome characterization advance regenerative medicine? Share your thoughts in the comments section below.

Up Next: Explosion of Interest In Exosome Technologies And Companies Leading The Charge

Footnotes
[1] Search on PubMed.gov. Search Term: “exosome” or “exosomes”. Date of Search: December 1, 2017.
[2] Ncbi.nlm.nih.gov. (2017). “PLoS ONE” AND exosome – PubMed – NCBI. [online] Available at: https://www.ncbi.nlm.nih.gov/pubmed/?term=%22PLoS+ONE%22+AND+exosome [Accessed 12 Nov. 2017].
[3] Ncbi.nlm.nih.gov. (2017). “J Biol Chem” AND exosome – PubMed – NCBI. [online] Available at: https://www.ncbi.nlm.nih.gov/pubmed/?term=%22J+Biol+Chem%22+AND+exosome [Accessed 12 Nov. 2017].\

Editor’s Note: This post was originally published on October 11, 2018, and has been updated for quality and relevancy.

The market for stem cell exosomes is a fast-growth, high potential market. Currently in its early-stages, the market is readily posed for expansion. With a limited number of market competitors and few products in clinical-stage trials, the market is ripe for disruption by new competitors and new technologies. [Read more…]