Exosomes are extracellular vesicles (EVs) of endosomal origin that range in size between 30 and 150 nanometers. Exosomes are secreted by a wide range of cells, since virtually all living cells utilize exosome-mediated communication. Exosomes carry cell-specific cargos of proteins, lipids, and nucleic acids that are selectively taken up by recipient cells. [Read more…]

Exosome-related technologies have been developing rapidly over the past few years and substantial growth is expected for the market as they get integrated into the fields of liquid biopsy, precision medicine and regenerative medicine. In particular, cancer derived exosomes influence the invasive potential of cells by regulating angiogenesis, metastasis, and immunity, making them an extremely useful source of biomarkers for use in cancer detection, diagnosis, and therapeutic selection. [Read more…]

Exosomes are produced and secreted out by nearly all living cells and have been found to occur in nearly every bodily fluid. They are found abundantly in the growth medium of many cultured cells, such as B lymphocytes, dendritic cells, cytotoxic T cells, intestinal epithelial cells, neurons, oligodendrocytes, platelets, mast cells and Schwann cells. [Read more…]