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Home » The Booming Market for Exosomes in 2022
Exosomes Extracellular Vesicles Market

The Booming Market for Exosomes in 2022

January 24, 2022 By Cade Hildreth (CEO) Leave a Comment

Exosome-related technologies have been developing rapidly over the past few years and substantial growth is expected for the market as they get integrated into the fields of liquid biopsy, precision medicine and regenerative medicine. In particular, cancer derived exosomes influence the invasive potential of cells by regulating angiogenesis, metastasis, and immunity, making them an extremely useful source of biomarkers for use in cancer detection, diagnosis, and therapeutic selection.

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Exosomes are extracellular vesicles (EVs) of endosomal origin that range in size between 30 and 100 nanometers. Exosomes are secreted by a wide range of cells, since virtually all living cells utilize exosome-mediated communication. Exosomes carry cell-specific cargos of proteins, lipids, and nucleic acids that are selectively taken up by recipient cells.

Exosomes as Cell-Free Therapeutics, Engineered Drug Carriers, and Biomarkers

The cargo contained within exosomes can offer prognostic information for range of diseases—including cardiovascular, renal, neurodegenerative, and metabolic diseases—as well as cancer.  Researchers investigating exosome biomarkers have discovered, identified, and reported the presence of hundreds of biomolecules within the lumen of exosomes.

bitbio

This discovery has compelled a rapid rise in exosome-related cancer biomarker research, including the use of exosomes for the detection, monitoring, and treatment of a diverse range of oncologic conditions.

Importantly, exosomes are present within a diverse range of biofluids, including serum, plasma, urine, seminal fluid, CSF, saliva, tears and breast milk. For this reason, exosome-based diagnostics are minimally invasive, offering ease of use and speed of detection. Exosomes can also act as prognostic indicators and predictors of a patient’s response to a specific course of treatment.

Pluristyx

Exosomes are also being explored for their use as cell-free therapeutics. For example, if a patient has a disease caused by a missing or defective protein or microRNA, the patient’s exosomes can be isolated, modified with the appropriate siRNA or protein and then injected back into the patient for treatment.  There are also many approaches being researched for creating drug-loaded exosomes. Furthermore, exosomes can often exert powerful effects. For example, mesenchymal stem cell (MSC) derived exosomes have the capacity to suppress inflammation, prevent scar tissue formation, and mediate a healthy immune response.

Exosome Market Trends

For these reasons, exosomes have gone from being overlooked to rapidly gaining momentum as a novel strategy for accessing the therapeutic effects of cells without the risks and difficulties of administering cells to patients. Although exosomes were discovered more than 30 years ago, it was not until recently that the scientific community began to give credit to exosomes for a range of promising traits. Fifteen years ago in 2006, there  were only 76 articles published about exosomes on PubMed.gov.  Today, there an astounding 17,850 articles published about exosomes on PubMed.gov, of which the vast majority were released in the past five years.

When exosome publications are analyzed, U.S. authors have published approximately 40% of the articles and China comes in second place. When the term “exosome” is searched in the scientific literature, Dr. Susanne Gabrielsson from the Karolinska Institutet in Sweden is the leading author.

iPSC-derived cardiomyocte therapy

When the term “extracellular vesicles” is searched, Unicyte AG, a regenerative medicine unit of Fresenius Medical Care, takes the lead. Headquartered in Switzerland, the company has published more than 100 papers on exosomes and extracellular vesicles in combination with Professor Giovanni Camussi.

Exosome Market Forces

To characterize the rapidly expanding exosome market, BioInformant has released a 274-page global market report that explores growing demand for exosome therapeutics, diagnostics, research tools, and manufacturing technologies. The report reveals trend rate data for exosome patents, grants, scientific publications, and clinical trials.

It highlights information about exosome industry partnerships, merger and acquisition (M&A) activity, and financing events. It features company profiles for 107 global competitors from across the exosome marketplace. Importantly, it presents market size determinations by market segment with forecasts through 2028.

Today in 2022, the exosome industry is witnessing:

  • A surging number of scientific papers investigating exosomes and their applications
  • Rising numbers of clinicals trials investigating exosome therapeutics and diagnostics
  • Swelling appetite among investors for exosome technology
  • An increasingly competitive IP environment
  • A diverse range of co-development partnerships
  • Proliferating numbers of exosome competitors in all major life science markets worldwide

This global strategic report about the exosome industry reveals:

  1. The pipeline for exosome therapeutics
  2. Clinical trial activity by type, region, phase, and sponsor
  3. Exosome industry events, including M&A activity, financing events, and IPOs
  4. Strategic partnerships and co-development agreements
  5. Competitors composing the global marketplace, including core technologies and products under development
  6. Market size determinations by market segment, with forecasts through 2028
  7. Exosome industry trends, competitive opportunities, and future directions for the global market
  8. And so much more
To learn more about this rapidly expanding marketplace, view the “Global Exosome Market – Market Size, Forecast, Trials and Trends, 2022.”

Exosome Market Size | Exosome Market Report

5/5 - (3 votes)

Filed Under: Exosomes

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About Cade Hildreth (CEO)

Cade Hildreth is the Founder of BioInformant.com, the world's largest publisher of stem cell industry news. Cade is a media expert on stem cells, recently interviewed by the Wall Street Journal, Los Angeles Business Journal, Xconomy, and Vogue Magazine. 

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