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Home » market report

“Mesenchymal Stem Cells – Advances & Applications” — Market Size, Segments, Trends, & Projections through 2020

February 24, 2016 By Cade Hildreth (CEO) Leave a Comment

Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into a variety of cell types, including osteoblasts, chondrocytes, myocytes, adipocytes, and potentially other cell types. For years, it has been clear that MSCs are a leading type of stem cell being investigated for therapeutic applications, because they have the potential to treat a wide range of acute and degenerative diseases.

In addition to secreting factors that can stimulate tissue repair, MSCs can substantially alter their microenvironment, exerting effects that are both anti-inflammatory and anti-fibrotic. MSCs are also advantageous over other stem cells types, because they avoid the ethical issues that surround embryonic stem cell research and appear to be immuno-privileged.

Importantly, MSCs also well-suited for use in the exponential growth area of 3D printing, because of their unusual capacity to form structural tissues. [Read more…]

Filed Under: MSCs, Stem Cells Tagged With: market report, mesenchymal stem cells, metrics, projections, social analytics, trends

BioInformant Releases “Stem Cell Research Products – Opportunities, Tools, & Technologies” with Market Size, Segments, Trends, & Projections to 2020

February 10, 2016 By Cade Hildreth (CEO) Leave a Comment

BioInformant Releases “Stem Cell Research Products, Opportunities, Tools, & Technologies - Market Size, Segments, Trends, and Projections to 2020”

February 11, 2016; Washington, DC — BioInformant announces the February 2016 release of its global strategic report, “Stem Cell Research Products, Opportunities, Tools, and Technologies” with market size, segments, trends, and projections to 2020.

The first and only market research firm to specialize in the stem cell industry, BioInformant has more than a decade of historical information on all segments of the stem cell market, by stem cell type. This powerful 175 page global strategic report contains market size, segments, trends, and projections through 2020, as well a social analytics and an end-user survey of nearly 300 stem cell scientists. The “Survey of Stem Cell Scientists” identifies technical requirements, unmet needs, and purchasing preferences of stem cell researchers worldwide. [Read more…]

Filed Under: Adipose SCs, HSCs, iPS Cells, MSCs, Neural Stem Cells, Stem Cells Tagged With: market report, press release, research products, stem cells, STEMCELL Technologies, Thermo Fisher Scientific

Imagine Increasing Revenue from Stem Cell Products and Decreasing Risk

February 10, 2016 By Cade Hildreth (CEO) Leave a Comment

Imagine Increasing Revenue from Stem Cell Products and Decreasing Risk

We have helped hundreds of the top companies increase revenue from stem cell products and decrease risk. The key is targeted market intelligence, because it will help you to approach institutional investors for fundraising rounds, guide internal decision-making within your company, and reduce the risk that has traditionally accompanied new product development. Simply put, it will help you make smarter decisions, faster.

Whether or not you can invest in the recently released global strategic report, “Stem Cell Research Products – Opportunities, Tools, and Technologies,” the following is an important introduction to the stem cell research products marketplace, including key trends and future projections. [Read more…]

Filed Under: Adipose SCs, HSCs, iPS Cells, MSCs, Neural Stem Cells, Stem Cells Tagged With: Accellta, Cellular Dynamics International, cynata, market report, research products, RoosterBio, stem cells

Will Japan or the U.S. Dominate the Induced Pluripotent Stem Cell Market through 2020? 

December 15, 2015 By Cade Hildreth (CEO) Leave a Comment

induced pluripotent stem cells advantages | Will Japan or the U.S. Dominate the Induced Pluripotent Stem Cell Market through 2020?

One of the induced pluripotent stem cells advantages is that they are non-controversial, while being capable of turning into every cell type within the human body.

Stem cell research and experimentation have been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. Traditionally, scientists have worked with both embryonic and adult stem cells. While the appeal of embryonic stem cells (ESCs) has been their ability to differentiate into any type of cell, there has been significant ethical, moral, and spiritual controversy surrounding their use. On the other hand, adult stem cells are uncontroversial, but they can have a limited differentiation capacity, creating narrowed options for use.

Therefore, induced pluripotent stem cells are advantaged in that they display a promising combination of adult and embryonic stem cell characteristics.

A Look Into Induced Pluripotent Stem Cells Advantages

In this article:

  • Discovery of Induced Pluripotent Stem Cells (iPSCs)
  • Induced Pluripotent Stem Cells Issues
  • Accelerating Progress with Induced Pluripotent Stem Cells (iPSCs)
  • BioInformant’s “Induced Pluripotent Stem Cell Industry Report”
  • Key Report Findings

 

Discovery of Induced Pluripotent Stem Cells (iPSCs)

A groundbreaking experimentation in 2006 led to the introduction of induced pluripotent stem cells (iPSCs). These were adult cells that were isolated and then transformed into embryonic-like stem cells through the manipulation of gene expression, as well as other methods. Research and experimentation using mouse cells at Kyoto University in Japan were the first instances in which there was a successful generation of the iPSC. In 2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were transformed into iPSC cells.

Induced Pluripotent Stem Cells Issues

While there has been continued excitement at the prospect of what such artificially re-manufactured cells could contribute to medical advances, there have also been issues along the way. By 2010, there were a number of private companies that were ready to capitalize on the breakthrough technology that iPSCs represent. One such company, Advanced Cell Technology (now Ocata Therapeutics) discovered several problematic issues while conducting experiments for the purpose of applying for FDA approval to use iPSCs in therapeutic applications. Concerns such as premature cell death, mutation into cancer cells, and low proliferation rates were some of the problems that surfaced.

Nonetheless, the progress with iPSCs continued to accelerate within both private industry and academia, and recent years have been a time of massive change for the industry.

Accelerating Progress with Induced Pluripotent Stem Cells (iPSCs)

Cellular Dynamics International as The Global Leader for iPSCs

In a landmark event, Cellular Dynamics International (CDI) went public in July 2013 with an offering that raised $43 million dollars for the company, securing the company’s position as the global leader in producing high-quality human iPSCs and differentiated cells in industrial quantities. Also in 2013, Cellular Dynamics International and the Coriell Institute for Medical Research announced receiving multi-million-dollar grants from the California Institute for Regenerative Medicine (CIRM) for the creation of iPSC lines from 3,000 healthy and diseased donors, a result that will create the world’s largest human iPSC bank.

The First Human Transplant for iPSCs

Furthermore, 2013 was the first year in which clinical research involving transplant of iPSCs into humans was initiated, with Masayo Takahashi of the RIKEN Center in Japan investigating the safety of iPSC-derived cell sheets in patients with wet-type age-related macular degeneration. While the trial was initiated in 2013 and production of iPSCs from patients began at that time, it was not until August of 2014 that the first patient, a Japanese woman, was implanted with retinal tissue generated using iPSCs derived from her own skin cells. A team of three eye specialists, led by Yasuo Kurimoto of the Kobe City Medical Center General Hospital, implanted a 1.3 by 3.0mm sheet of iPSC-derived retinal pigment epithelium cells into the patient’s retina. Unfortunately, this trial has since been paused due to potential safety concerns, and its continued progress is “on hold” until these safety issues are resolved.

CDI’s cGMP HLA Superdonor Stem Cell Lines

By February 2015, Cellular Dynamics International had announced continued innovation with iPSCs, stating that it would be manufacturing cGMP HLA “superdonor” stem cell lines that will support cellular therapy applications through genetic matching. Currently, CDI has two HLA superdonor cell lines that provide a partial HLA match to approximately 19% of the population within the U.S., and it aims to expand its master stem cell bank by collecting more donor cell lines that will cover 95% of the U.S. population. The HLA superdonor cell lines were manufactured using blood samples and used to produce iPSC lines, giving the cells the capacity to differentiate into nearly any cell within the human body.

Announcement For the Opening of iPSC Therapy Center

Also in February 2015, Kyoto University Hospital in Kobe, Japan, announced it would be opening an iPSC therapy center by 2019, for purposes of conducting clinical studies on iPSC therapies. The announcement further positioned Japan as the leading nation committed to bringing iPSC therapies to clinics. Officials for Kyoto Hospital said it will open a 30-bed ward to test the efficacy and safety of the therapies on volunteer patients, with the hospital aiming to initiate construction at the site in February of 2016 and complete construction by September 2019.

FUJIFILM Holdings Corporation’s Acquisition of CDI

By March 2015, FUJIFILM Holdings Corporation had acquired Cellular Dynamics International (CDI) for $307 million, making CDI a holding company underneath its multinational Japanese parent company. FUJIFILM Holdings is a multinational company headquartered in Tokyo that has historically been known as a photography and imaging company. However, it recently re-positioned itself to become a major stakeholder in the regenerative medicine industry. In addition to acquiring CDI, FUJIFILM has been gradually increasing its reach within the regenerative medicine field, with another notable acquisition being the majority position that it took in Japan Tissue Engineering Co., Ltd., in December 2014.

The Introduction of ORIG3N in the iPSC Market

Finally, a small American biotechnology company, ORIG3N, is now bringing iPSC banking directly to the public through its creation of the world’s largest blood cell repository for iPSC production. Founded in April 2014 and funded by a February 2015 investment of $3.1 million from an investor syndicate led by Hatteras Venture Partners, ORIG3N has been doing this through an innovative program called “LifeCapsule,” in which individuals can store their own iPSCs for future regenerative medicine needs.

In summary, major advances in iPSC clinical research applications, production and differentiation technologies, and biobanking have been seen in recent years. It is clear that iPSCs are a vital research trend within the scientific community and that the cells represent a promising tool for use in the reversal and repair of many previously incurable diseases.

Market Metrics and End-User Survey Results from iPSC Researchers

Since their discovery in 2006, a large and thriving research products market has grown into existence for iPSCs. Indeed, the number of iPSC research products sold worldwide has been growing at a double-digit rate, and 22% of all stem cell researchers now self-report as having used induced pluripotent stem cells within a research project. It is clear that iPSCs are a vital research trend within the scientific community.

BioInformant’s “Global Induced Pluripotent Stem Cell Industry Report”

To assess opportunities and threats within the rapidly changing iPSC marketplace, BioInformant recently released a global strategic report: the “Complete 2015-16 Induced Pluripotent Stem Cell Industry Report.”

A distinctive feature of this report is an end-user survey of 274 researchers (131 U.S./143 International) that identify as having induced pluripotent stem cells as their core research focus. These survey findings reveal iPSC researcher needs, technical preferences, key factors influencing buying decisions, and more. Therefore, they can be used to make effective product development decisions, create targeted marketing messages, and produce higher prospect-to-client conversion rates.

Key Report Findings

Furthermore, this 2015 report contains 175 pages of detailed industry analysis, including:

  • Charts, Timelines, and Forecasts for the iPSC Market
  • Trend Rate Data for iPSC Grants, Scientific Publications, Clinical Trials, and Patents
  • Market Size Determinations, with 5-Year Forecasts
  • Competitive Environment Analysis, including Market Share by Competitor
  • Preferred Species for iPSC Research
  • Breakdown of Market Share by iPSC Product Category
  • Consumer Behavioral Patterns
  • Preferred Providers of iPSC Products
  • Crucial Trends and Unmet Market Needs
  • “Tested Sentences” for Selling to iPSC Scientists
  • Breakdown of the Marketing Methods Used by Industry Participants
  • End-User Survey of iPSC Researchers (131 U.S. / 143 International)

In summary, the “Global Complete 2015-16 Induced Pluripotent Stem Cell Industry Report” is a must-read industry report for executives and investors to optimally position themselves to sell iPSC products. To profit from this lucrative and rapidly expanding market, you need to understand your key strengths relative to the competition, intelligently position your products to fill gaps in the marketplace, and take advantage of crucial iPSC trends.

Remember, all BioInformant products come with a “Greater than 100% Money Back Guarantee.” If the strategies and tools aren’t helpful to you, then we will cheerfully refund your money and you can keep the product.

Claim this report now to profit from this expanding market – or your competition will.

What other induced pluripotent stem cells advantages should be added to this article? Share them in the comments section.

Up Next: Cell Symposia to Host “Translation of Stem Cells to the Clinic” | Dec 2-4 in Los Angeles

Filed Under: HSCs, iPS Cells, MSCs, Stem Cells Tagged With: Cellular Dynamics International, iPSC, market metrics, market report, Ocata Therapeutics, ReproCELL, stem cells

BioInformant Releases Mesenchymal Stem Cell Industry Report with Traditional Metrics and New Social Analytics

November 21, 2015 By Cade Hildreth (CEO) Leave a Comment

BioInformant Releases Mesenchymal Stem Cell Industry Report with Traditional Metrics and New Social Analytics

View on PRNewswire or read the full press release below.

PRESS RELEASE; Washington, DC; November 21, 2015 — BioInformant, the only market research firm to exclusively serve the stem cell sector, announces the release of its global strategic report, “Mesenchymal Stem Cells – Advances and Applications.” Published November 2015, it presents 250 pages of coverage for the rapidly-evolving mesenchymal stem cell (MSC) industry.

Called the “most innovative market research firm in the world,” BioInformant tracks MSC industry metrics using continuously maintained dashboards combined with systems to trigger alerts when data exhibits unexpected variation.

A unique attribute of BioInformant is that its management team comes from a BioInformatics background – the science of collecting and analyzing complex biological data. BioInformant is the only known research firm to apply these data analysis techniques to the field of market research. This is important, because 2015 saw the first “thaw and use” ink to make MSCs readily available for 3D printing (RoosterBio and CELLINK), a novel manufacturing approach to produce a nearly unlimited supply of MSCs from iPSCs derived from a single donor (Cynata Therapeutics), and the recommendation for approval of a MSC product in Japan (JR-031 developed by Mesoblast’s Japanese partner, JCR Pharmaceuticals Co. Ltd). It is clear that the scope of the MSC industry is expanding and advanced analytics are required.

The report describes the current status of MSC research, the ongoing clinical trials involving MSCs, late stage MSC clinical trials, and possible uses of MSCs in cell therapy. Because MSCs are a sub-segment of the broader cell therapy (CT) and regenerative medicine (RM) markets, it also gives an overview of the regenerative medicine industry and overall cell therapy industry.

Importantly, BioInformant is always innovating. It tracks traditional market metrics, which include trend rate data for MSC clinical trials, scientific publications, grants, patents, product launches, new market entrants, acquisitions, and industry deal-making. However, it also tracks recently discovered social analytics, which are metrics derived from social media sites, search engines, online advertising platforms, and more. It is the only known research firm to take this duel-approach to market analysis.

Founded in 2006 in Washington, DC, BioInformant is distinctively suited to tracking the MSC industry, because it has been following the industry for a decade, providing a robust database of historical data.

BioInformant research has been cited on prominent news outlets that include the Wall Street Journal, Nature Biotechnology, CBS News, Medical Ethics, the Center for BioNetworking, and more. BioInformant also serves notable clients across the stem cell spectrum, with Fortune 500 companies on its client list that include GE Healthcare, Pfizer, Goldman Sachs, Beckton Dickinson, and many more.

Click here to view the full Executive Summary and Table of Contents: https://bioinformant.wpengine.com/product/mesenchymal-stem-cells-advances-and-applications/.

About BioInformant

In addition to offering cutting-edge market intelligence, BioInformant operates a stem cell industry blog at www.BioInformant.com which is nearing 100K views per month and has a subscriber base of stem cell industry executives and investors approaching 10K. It is a company goal to reach 500K views by mid-2017.  BioInformant’s President/CEO, Cade Hildreth, is a media expert on stem cell industry topics, recently conducting interviews with the Wall Street Journal and Los Angeles Business Journal.

Press Contact

Cade Hildreth, President/CEO
Hildreth@BioInformant.com
703-859-7617

Filed Under: Cord Blood, MSCs, Stem Cells Tagged With: cellink, cynata, market report, mesenchymal stem cells, metrics, press release, product launch, RoosterBio, social analytics

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