Happy Holidays! I hope you are enjoying this exciting season with family, friends, colleagues, and lots of holiday cheer. As you celebrate and reflect on a prosperous 2016, we have posted new stem cell industry coverage to help you prepare for 2017. This week in stem cells we cover cell therapy in Asia, exosomes going exponential, a massive $225M series A financing, and much more. [Read more…]
The Exosome Revolution is Here
Exosomes have recently exploded in popularity, with companies developing exosome-based diagnostics, therapeutics, and cosmeceuticals. Although they were discovered more than 30 years ago, it was not until recently that the scientific community began to give credit to exosomes for a range of promising traits.
Exosomes are small vesicles ranging from 30-100nm in size that are found in nearly all eukaryotic fluids and facilitate a range of important cellular functions. Specifically, they transfer DNA, RNA, and proteins to other cells, thereby altering the function of the targeted cells.
Exosome History: A Recent Explosion of Interest
Ten years ago in 2006, there were only 76 articles published about exosomes (PubMed.gov: Date Range: Jan 1, 2006 to Dec 31, 2006). Five years ago in 2011, there were 271 articles published about exosomes (PubMed.gov: Date Range: Jan 1, 2011 to Dec 31, 2011).
Today, there are more than 4,400 articles published about exosomes. Importantly, 1,088 of the articles (~25%) were released in the 2016 calendar year. [Read more…]
Role of MSC-Derived Exosomes in Healing the Injured Spinal Cord – Interview with Dr. Askenase
This is an interview with Philip Askenase, MD, Professor of Medicine and Pathology at Yale University School of Medicine. Dr. Askenase is an expert in the effector properties of exosomes who is now beginning to study mesenchymal stem cell (MSC)-derived exosomes and their role in regenerative processes.
Specifically, Dr. Askenase’s new unpublished preliminary work is focused on the role of MSC-derived exosomes in healing the injured spinal cord in rats.
In this interview, we discuss the growing importance of MSC-derived exosomes, including their advantages and applications. We also explore the market potential for stem cell exosomes, as well as companies competing in this emerging market area.
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