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Home » Stem Cells » Page 4

How Human iPSCs are Revolutionizing Drug Discovery in 2022

May 3, 2022 By Cade Hildreth (CEO) Leave a Comment

ipsc drug discovery

Drug discovery involves high cost and uncertain outcomes.  Only a few companies can take the risk of investing enormous amounts of money into research and testing, only to see undesirable side effects emerge during the final human clinical trials. In many cases, companies are spending millions of dollars to fail during clinical testing.

Now, some new medicines are being tested for safety on specialized cells developed from human pluripotent cell lines. Cell types which are frequently being using within drug discovery applications include heart (cardiomyocytes) and liver cells (hepatocytes), which are the organs where 80% of drug failures occur. [Read more…]

Filed Under: iPS Cells Tagged With: drug discovery

Cell Therapy Manufacturing | Factors Driving Interest in Cell Therapy CDMOs

May 2, 2022 By Cade Hildreth (CEO) Leave a Comment

Cell Therapy CMO CDMO

Cell therapy manufacturing is becoming of growing importance as more and more cell therapeutics make their way through clinical trials. One of the major issues with moving cell therapy products from “bench to bedside” has been manufacturing bottlenecks. The heterogeneous nature of cell therapy products has introduced manufacturing complexity and regulatory concerns, as well as scale-up complexities that are not present within traditional pharmaceutical manufacturing.

Cell Therapy Manufacturing CDMOs

While these realities may sound like negative factors for the industry, the reality is quite the opposite. For cell therapy CDMOs, these factors create pressures for cell therapy companies to seek third-party partners who possess technical, manufacturing, and regulatory expertise in cell therapy development and manufacturing. [Read more…]

Filed Under: Stem Cells Tagged With: CDMO, cell therapy

Stem Cell Therapy For Knees

May 2, 2022 By Cade Hildreth (CEO) 4 Comments

Feature | Stem Cell Therapy For Knees

Stem cell therapy for knees has the potential to provide relief to a lot of people. Knee pain is an common condition that affects millions of Americans and people around the world. Considering the daily load that legs bear, a problem with your knees can limit movement. Knee pain can substantially reduce your quality of life and anti-inflammatory medication can only do so much. Suffice it to say, there exists significant interest in finding solutions to address knee pain and to restore healthy joint function.

That’s where stem cell therapy for knees comes in. [Read more…]

Filed Under: Cell Therapy, Stem Cells

Can We Extend the Human Lifespan With Regenerative Medicine?

May 1, 2022 By Cade Hildreth (CEO) 3 Comments

Regenerative Medicine

Regenerative medicine is a fascinating topic, because it requires you to ask yourself: Would you want to live to be 200 years old? A scientist from Stanford University thinks that it’s possible – so much so that he has placed a bet that there is someone alive today who will live to be 200 years old.

Over recent decades, modern scientific developments have led to a dramatic increase in human lifespan. But how much further can we go? Does regenerative medicine have the power to enable us all to live for many more years?

Let’s dive into this fascinating topic and find out more about regenerative medicine. How could it extend human life into the future? [Read more…]

Filed Under: Stem Cells

Ncardia Launches Cellistic™, the Only iPSC-based Cell Therapy Process Development & Manufacturing Partner Purpose-built to Make Large-scale Allogeneic Cell Therapy Production a Reality Today

April 26, 2022 By Cade Hildreth (CEO) Leave a Comment

Ncardia Cellistic

GOSSELIES, Belgium, April 19, 2022 – Ncardia has launched a new business, Cellistic™, to focus Ncardia’s induced pluripotent stem cell (iPSC) expertise on the cell therapy development and manufacturing sector. This strategy expands on Ncardia’s existing drug discovery solutions business and capitalizes on the company’s deep expertise in iPSC differentiation and expansion to focus dedicated resources and capabilities to address the growing need for iPSC cell therapy solutions, including the development of robust cell-specific manufacturing platforms. [Read more…]

Filed Under: iPS Cells, Press Releases, Stem Cell News, Stem Cells

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