Umbilical cord blood (UCB) has been an accepted source of hematopoietic stem cells (HSC) for transplantation for more than 30 years. Umbilical cord-derived stem cells are the youngest cells available for transfusion and yet their uptake lags behind bone marrow and peripheral blood-derived HSCs. Decreased engraftment rates and the low cell dose available for transplantation are limitations that are preventing umbilical cord blood-derived cells from reaching their full potential. While a handful of companies are now developing cord blood and tissue-derived cell therapeutics, it will likely take several years for these products to reach commercialization. [Read more…]
Cord Blood
Because cord blood present within a newborn’s umbilical is rich with stem cells, it can be collected and stored for future medical use.
Evolution of the Umbilical Cord Blood and Tissue Banking Market in 2023 and Beyond
The first transplant using cord blood-derived hematopoietic stem cells was performed in October 1988. Since that year, remarkable achievements have been made in terms of research into umbilical cord blood-derived hematopoietic and progenitor cells. More than 40,000 UCB transplants (UCBTs) have been performed across different geographies of the world, in both children and adults, to treat diseases that include hematologic, metabolic, immunologic, neoplastic, and neurologic disorders. [Read more…]
First Patient Dosed with Gamida Cell’s Expanded Cord Blood Cell Therapy, Omisirge™
Omisirge is the world’s 1st U.S. FDA approved product that is a expanded umbilical cord blood cell therapy.
It is also the only allogeneic stem cell therapy approved by the U.S. FDA on the basis of a global randomized Phase 3 trial.
Rapid onboarding of transplant centers and significant payer coverage demonstrate strong launch progress.
Boston, MA, September 27, 2023 –– Gamida Cell Ltd. (Nasdaq: GMDA), a cell therapy pioneer working to turn cells into powerful therapeutics, announced that the first patient has received a stem cell transplant with Omisirge (omidubicel-onlv). [Read more…]
The History of Cord Blood Transplantation
The history of cord blood banking is fascinating, because the service did not exist on a widespread basis until a few decades ago. Below, we introduce key historical events that have affected cord blood and cord tissue storage, both in the U.S. and worldwide.
[Read more…]
Cord Blood and Tissue Banking: 14 Terms to Define
Since the first stem cell transplant occurred more than 65 years ago (1957), there has been a nearly exponential increase in stem cell transplants, and in late 2012, the millionth stem cell transplant occurred, a landmark event in stem cell medicine. It is clear that the stem cells contained within cord blood banking now have the potential to improve and save lives. Since the first cord blood transplant was performed in 1988, stem cells derived from umbilical blood have been used in more than 40,000 transplants worldwide. [Read more…]
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