Multipotent stem cell research has come into the mainstream, as regenerative medicine exits its infancy and begins to take hold in major healthcare markets worldwide. The possibilities inherent in multipotent stem cells – those capable of turning into a wide variety of different bodily cells – make it one of the most exciting developments today. [Read more…]
Types of CAR-T Cells: Improvements in CAR Design and Construction
What are the types of CAR-T cells and how have they changed in recent years? CAR-T cells are immune cells that are artificially engineered to express a particular chimeric antigen receptor (CAR), which have shown great potential in killing cancer cells. Chimeric antigen receptors (CARs) are artificially produced recombinant receptors having both antigen-binding and T-cell activating potentials.
CARs are composed of an extracellular recognition domain sourced from monoclonal antibodies (mAbs) and an intracellular signaling domain including CD3- and costimulatory domains for triggering endogenous signaling pathways of T-cells. [Read more…]
Caribou Biosciences Granted FDA RMAT and Fast Track Designations for CB-010, an Allogeneic Anti-CD19 CAR-T Cell Therapy
RMAT and Fast Track designations follow CB-010’s durable complete responses at dose level 1 in the ANTLER Phase 1 trial
CB-010 is the 1st allogeneic CAR-T cell therapy in the clinic with a PD-1 knockout
Stem Cell Treatments For Lungs? Paths to Relief and Recovery
Lung diseases can be debilitating, making both medical leaders and patients interested in exploring stem cell treatments for lungs. Find out what you need to know about stem cell therapy for lungs, including risks, benefits, clinical trial progress and more. [Read more…]
Stem Cell Therapy For Knees
Stem cell therapy for knees has the potential to provide relief to a lot of people. Knee pain is an common condition that affects millions of Americans and people around the world. Considering the daily load that legs bear, a problem with your knees can limit movement. Knee pain can substantially reduce your quality of life and anti-inflammatory medication can only do so much. Suffice it to say, there exists significant interest in finding solutions to address knee pain and to restore healthy joint function.
That’s where stem cell therapy for knees comes in. [Read more…]
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