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Xintela’s stem cell product XSTEM shows safety and sustained positive efficacy results two years after treatment in knee osteoarthritis clinical study

October 9, 2025 By BioInformant Team Leave a Comment

The final analysis including the 24-month evaluation of Xintela’s (XINT) clinical study on XSTEM for knee osteoarthritis has now been completed. The results show continued safety, reduction of knee pain, improved joint function, and improvements in bone and cartilage structure. This confirms a sustained treatment effect in knee osteoarthritis and supports a disease-modifying effect of XSTEM. Xintela has previously communicated positive interim results up to 18 months after treatment of knee osteoarthritis patients with three dose levels of XSTEM. The highest dose level, which showed the best results after 18 months, has now shown sustained positive treatment effects two years after XSTEM treatment.

XSTEM, which consists of allogeneic (donated) integrin α10β1-selected mesenchymal stem cells, is developed and manufactured by Xintela. [Read more…]

Maryland Governor Wes Moore to Speak at TEDCO’s 2025 Entrepreneur Expo

October 9, 2025 By BioInformant Team Leave a Comment

Join us in College Park on October 21 during the lunch keynote session

COLUMBIA, Md., Sept. 29, 2025 — TEDCO, Maryland’s economic engine for technology companies, announces the attendance of Maryland Governor Wes Moore at the upcoming 2025 Entrepreneur Expo. The premier event will take place at The Hotel at the University of Maryland on October 21, 2025. Gov. Moore will be making a special appearance during the lunch keynote session. [Read more…]

The Global Stem Cell Market and What It Means for Students Considering STEM Careers

October 9, 2025 By Marie Carroll Leave a Comment

As the field of medical research accelerates, stem cell technology stands at the forefront of innovative treatment options and scientific discovery. The global stem cell market is projected to surpass significant financial milestones, making it a hot topic in both the scientific community and the business world. For students contemplating careers in science, technology, engineering, and mathematics (STEM), this growing market offers both exciting possibilities and serious considerations as they shape their educational paths. [Read more…]

What are Perinatal Stem Cells? Your Definitive Guide

October 6, 2025 By Cade Hildreth, Founder & President Leave a Comment

Perinatal stem cells are obtained around the time of birth, either shortly before or after. They can be sourced from umbilical cord blood and tissue, placental blood and tissue, as well as amniotic fluid and tissue.

When stem cells were first identified, only two types of stem cells were described: embryonic stem cells and adult stem cells. Today, a diverse range of stem cells exist, because the diversity of adult stem cell types has substantially expanded and induced pluripotent stem cells (iPSCs) have since been discovered. [Read more…]

Qihan Biotech’s QN-139b becomes First iPSC-derived CAR NK therapy for Autoimmune Disease

October 6, 2025 By BioInformant Team Leave a Comment

A new chapter is beginning for iPSCs: Qihan Biotech, a leading innovator in cell engineering, has reported the first clinical use of an induced pluripotent stem cell (iPSC)-derived CAR natural killer (NK) therapy in an autoimmune disease. The product, known as QN-139b, was administered to a patient with refractory systemic sclerosis (SSc), marking the first time an iPSC-derived CAR immune therapy has been used beyond oncology. [Read more…]