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Home » CYP-001

Cynata Introduces Critical Innovation into MSC Manufacturing

June 8, 2017 By Cade Hildreth (CEO) Leave a Comment

Cynata Introduces Critical Innovation into MSC Manufacturing Process

In the context of cell therapy, product innovation is the introduction of a cellular product that is new or has significantly improved characteristics or intended uses. Over the past decade, a great deal of attention has been given to cell therapy product innovation, as demonstrated by the thousands of cell therapy products that have now entered clinical trials worldwide.

In contrast, process innovation refers to the implementation of a new or significantly improved production or delivery method. In the context of cell therapy, process innovation has received much less attention from the marketplace. [Read more…]

Filed Under: MSCs, Stem Cell News Tagged With: cynata therapeutics, CYP-001, news

Patient Treatment Commences in Cynata’s World First Clinical Trial (CYP-001)

May 16, 2017 By Cade Hildreth (CEO) 1 Comment

Cynata CYP-001 Clinical Trial
  • First patient with steroid resistant acute graft-versus-host disease (GvHD) treated in Cynata’s phase 1 clinical study of its mesenchymal stem cell (MSC) product, CYP-001
  • World first clinical trial using a MSC therapeutic product derived from an induced pluripotent stem cell sourced from a single blood donation from one donor
  • Transition into active clinical trials cements Cynata’s world leading position in the development and commercialisation of second generation stem cell products
  • Partnership with Fujifilm for the commercialisation of CYP-001; trial commencement accelerates this target

[Read more…]

Filed Under: iPS Cells, MSCs Tagged With: clinical trial, cynata, CYP-001, MSC

Cynata Therapeutics Secures $6M in Capital Raise, $10M with Payment from FUJIFILM

January 24, 2017 By Cade Hildreth (CEO) Leave a Comment

Cynata - Capital Raise of $6M

Cynata Successfully Completes Capital Raising

Cynata TherapeuticsMelbourne, Australia; 23 January 2017: Australian stem cell and regenerative medicine company, Cynata Therapeutics Limited (ASX: CYP), has successfully completed a placement of approximately 9.23 million fully-paid ordinary shares at a price of $0.65, for gross proceeds of A$6.0 million before costs (“Placement”). The Placement was made to existing and new sophisticated and institutional investors. Settlement of the Placement, which was heavily over-subscribed, is expected to occur on or about 27 January 2017 with the shares to be issued on 30 January 2017. The Placement shares will be issued under Cynata’s existing placement capacity under Listing Rules 7.1 and 7.1A, and accordingly will not require shareholder approval.  [Read more…]

Filed Under: iPS Cells, MSCs Tagged With: cynata, CYP-001, financing, iPSC

Cynata Inks Deal with FUJIFILM, $3.97M Plus Potential Payments of $60M+

January 19, 2017 By Cade Hildreth (CEO) Leave a Comment

Cynata and FUJIFILM Sign Development and Commercialisation Partnership Agreement

  • Fujifilm takes A$3.97 million strategic equity stake in Cynata
  • Parties to collaborate on the further development and commercialisation of Cynata’s lead Cymerus™ therapeutic MSC product CYP-001 for graft-versus-host disease (GvHD)
  • Potential future upfront and milestone payments in excess of A$60 million
  • Double-digit royalties on CYP-001 product net sales
  • Strategic relationship for potential future manufacture of CYP-001 and certain rights to other Cynata technology

[Read more…]

Filed Under: iPS Cells, MSCs Tagged With: cynata therapeutics, CYP-001, FUIJFILM, MSC

UK Regulatory Authority Approves Cynata Therapeutics’ Phase I GvHD Clinical Trial

September 20, 2016 By Cade Hildreth (CEO) Leave a Comment

Cynata Therapeutics Phase I Clinical Trial Approved
  • UK regulatory authority MHRA approves Phase 1 trial with Cymerus(TM) MSCs
  • World first clinical trial with allogeneic iPSC-derived product
  • Major milestone for stem cell therapeutics and regenerative medicine
  • Cements Cynata’s global leadership in second generation MSC therapeutics

[Read more…]

Filed Under: iPS Cells, MSCs, Stem Cells Tagged With: clinical trial, cynata therapeutics, CYP-001, GvHD

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