Melbourne, Australia; 5 September 2016 — Australian stem cell and regenerative medicine company, Cynata Therapeutics Limited (ASX: CYP), announced the execution of a term sheet with FUJIFILM Corporation of Japan for the development and commercialisation of certain Cynata technology, including Cynata’s lead induced pluripotent stem cell (iPSC) derived therapeutic mesenchymal stem cell (MSC) product, CYP-001. Pursuant to the term sheet, the parties will work together to seek to finalise a definitive agreement. If the parties enter into a definitive agreement, Cynata expects it to be finalised in the fourth quarter of 2016. [Read more…]
Cynata Shares Jump as Japan’s FUJIFILM Negotiates Deal to Commercialize Cymerus™ Stem Cell Technology
Cynata Therapeutics (ASX: CYP) has executed a term sheet with FUJIFILM Corporation of Japan for the development and commercialisation of certain Cynata technology, including Cynata’s lead product, CYP-001. CYP-001 is an induced pluripotent stem cell (iPSC) derived mesenchymal stem cell (MSC) product that is anticipated to be the first allogeneic iPSC product to enter a clinical trial.
Dominance of Cellular Dynamics International (CDI) within iPSC Marketplace
Cellular Dynamics International (CDI), a FUJIFILM company, is the largest provider of induced pluripotent stem cell (iPSC) products worldwide. iPSCs are a type of laboratory made stem cell that has significant potential for use within regenerative medicine.
Theoretically, iPSCs have the potential to treat a wide range of diseases, including diabetes, heart diseases, autoimmune diseases, neural decline and more. iPSCs are also being widely implemented for use in drug development and discovery, as well as toxicology screening and personalized medicine.
In this article:
- Life Science Business Unit
- iPSC Market Competitors
- Cellular Dynamics International, Owned by Fujifilm Holdings
- Cellular Dynamics and Shinya Yamanaka
- Cellular Dynamics International Product Licenses
- An Important Player in Stem Cell Research and Therapy
- Use of iPSCs in Drug Development and Discovery
- CDI’s Acquisition by FUJIFILM Holdings Corporation
- The Advantage of Cellular Dynamics’ Fujifilm Acquisition
- Where Will CDI Focus iPSC Cell Production Technology?
Cellular Dynamics International and iPSC Therapy
Since September 2016, Cellular Dynamics International (CDI) has been divided into two business units, a Therapeutics Business Unit and a Life Science business unit. CDI’s Therapeutics business unit is focused on developing induced pluripotent stem cell (iPSC) based therapies for ocular, cardiac, neural and oncology applications. In contrast, CDI’s Life Science business unit is focused on developing the research products side of the business.
iPSC Market Competitors
In addition to CDI, there are many other companies and organizations that are involved with the development of induced pluripotent stem cell (iPSC) therapies, including but not limited to:
- Ocata Therapeutics
- RIKEN
- Kyoto University and CiRA
- Fate Therapeutics
- Megakaryon Corporation
- Cynata Therapeutics
There are also a number of companies specializing in iPSC product development, including:
- Allele Biotechnology
- ALSTEM Bio
- Applied Biological Materials (ABM)
- Applied StemCell
- Axol Bioscience
- BrainXell
- Cell Applications
- Cellular Dynamics International (a Fujifilm Company)
- EMD Millipore
- Minerva Biotechnologies
- Ncardia (formed through merger of Axiogenesis and Pluriomics)
- Neucyte
- Pluricell Biotech
- REPROCELL
- Sigma Aldrich (provides 350 iPSC lines through partnership with EBiSC)
- STEMCELL Technologies
- Stemgent (iPS Cell Business Unit owned by ReproCELL)
- Takara Bio
- Tempo Bioscience
- Thermo Fisher Scientific
- xCell Sciences
- And others
Fujifilm Cellular Dynamics Inc
Cellular Dynamics International is one of the most important market participants in the iPSC sector, because of its dominance in both iPSC therapies and life science tools.
European Society of Cardiology (ESC) Congress Presentation Reveals Results From Pre-Clinical Study Using CardioCell’s Stem Cells for Acute Myocardial Infarction
Data Indicate Administering Ischemia-Tolerant Mesenchymal Stem Cells (itMSCs) Intravenously Improves Cardiac Function Following an AMI
ROME, ITALY – EUROPEAN SOCIETY OF CARDIOLOGY CONGRESS 2016 – Aug. 29, 2016 – Study sponsor CardioCell LLC, a global biotechnology company that uses allogeneic stem cells for cardiovascular indications, announces data from its pre-clinical study “Mesenchymal stem cells grown under chronic hypoxia traffic to regions of myocardial infarction, suppress splenic natural killer cells, and attenuate adverse remodeling in mice with large acute MI” at the European Society of Cardiology (ESC) Congress.
Paper Co-Author Dr. Michael Lipinski, Interventional Cardiologist at MedStar Washington Hospital Center, presents the study that was designed in collaboration with Drs. Dror Luger, Research Scientist at Washington Hospital Center and Stephen Epstein, Director, Translational and Vascular Biology Research at MedStar Heart and Vascular Institute, Chair of CardioCell’s Scientific Advisory Board and Member of CardioCell’s Heart Failure Advisory Board. [Read more…]
Are You Attending the Axiogenesis iPSC Applications Workshop on September 7-9, 2016?
Recently, Axiogenesis hosted an American symposium titled, “iPSC Derived Cells & Assays Come of Age.” Held on June 13, 2016, in Boston, Massachusetts, the symposium explored the topic of establishing global standards for iPSC-derived cell products. Because the conversation is critical to a wide range of stem cell industry stakeholders, it was widely attended by representatives from across the pharmaceutical, biotechnology, and chemical sectors.
To further support this dialog within the global marketplace, Axiogenesis is hosting Human iPSC Applications Workshop in Cologne, Germany on September 7 – 9, 2016. It will be the fourth year that Axiogenesis has organized a workshop at its headquarters in Cologne. [Read more…]
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