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Cord Blood Industry Consolidation Escalates as 2020 Approaches

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The global cord blood industry experienced strong growth from the early 1990’s through the mid 2000’s, during which time more than 450 cord blood banking companies emerged worldwide. Approximately half of those companies owned their own labs, while the others were marketing entities or sub-contractors of storage space.

Starting about ten years ago, the market suddenly changed course. It entered a period of aggressive consolidation.

Over the past decade, the cord blood industry has witnessed substantial consolidation, particularly within the United States, Europe, and Latin America.

With CBR’s recent acquisition of Natera’s Evercord™ Cord Blood Business on September 13, 2019, the trend of cord blood industry consolidation continues. [Read more…]

Where Do Stem Cells Come From? | Basics Of Stem Cell Therapy

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Where do stem cells come from? Learn the basics of master cells to better understand their therapeutic potential.

In this article:

  1. An Introduction to Human Stem Cells
  2. Types of Stem Cells
  3. Where Do Stem Cells Come From?
  4. The Donation Process
  5. What Can Stem Cells Treat?
  6. Stem Cells for Testing New Drugs
  7. The Benefits of Stem Cell Transplant
  8. The Survival Rate of Stem Cell Therapy

[Read more…]

Will I See You at Phacilitate Leaders World 2020 (Psst, Get 10% Off)

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Advanced therapy companies have been rapidly populating over the past few years, making it a high-value, fast-growth industry. Key drivers include high rates of clinical trials, accelerated pathways for product approvals, new technologies to support cell and gene therapy manufacturing, and the potential for advanced therapies to revolutionize healthcare.

Stem Cell Industry Growth

Stem cell treatments are one of several segments that compose the advanced therapies industry, which includes but is not limited to cell therapy, gene therapy, and tissue engineering applications.

Stem cells have gained tremendous momentum over the last decade. As of November 2019, stem cell scientific publications have reached over 364,930 worldwide, with 25,000+ now being published per year.

Number of Stem Cell Scientific Publications Worldwide

For stem cell clinical trials, 7,400+ have been registered on ClinicalTrials.gov. Because this registry includes approximately 3/4ths of clinical trials worldwide, the total number of stem cell clinical trials worldwide is estimated to be approaching 10,000.

[Read more…]

100+ Current and Future Uses of Umbilical Cord Stem Cells

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Umbilical cord stem cells are present within the cord that connects a newborn to its mother and uses of these birth cells include treating cancers, diseases, injuries, and more. Umbilical cord blood contains hematopoietic stem cells (HSCs), which are multipotent stem cells that can give rise to other blood and immune system cells.

Stem cells can also be collected from a newborn’s:

  • Umbilical cord tissue (Wharton’s jelly)
  • Placenta
  • Amnion

Most commonly, hematopoietic stem cells (HSCs) from cord blood are used to treat blood cancers, such as leukemia. When compared to hematopoietic stem cells from genetically matched bone marrow donor, cord blood HSCs may provide some medical advantages, including fewer immune system complications, such as graft-versus-host disease (GvHD).

In recent years, regenerative medicine has continued to increase the list of medical uses for stem cells from umbilical cord. Find out more about current and future uses of umbilical cord stem cells below.

In this article:

  1. Current Uses of Stem Cells
  2. Potential Uses for Stem Cells

[Read more…]

Magenta Therapeutics Awarded an FDA RMAT for MGTA-456

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On September 4, 2019, Magenta Therapeutics announced it had received an FDA Regenerative Medicine Advance Therapy (RMAT) designation for MGTA-456, an expanded CD34+ cell therapy treatment used in place of single umbilical cord blood (UCB) transplantation. This one-time stem cell treatment is being investigated for the treatment of multiple inherited metabolic disorders. While there are 36 publicly announced RMAT designations, the FDA states that 40 or more have been awarded to date. [Read more…]

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