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What is the difference between totipotent, pluripotent, and multipotent?

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A common question is, what is the difference between totipotent, pluripotent, and multipotent cells? The answer is simple. Totipotent stem cells are the most versatile stem cell type, because they are formed shortly after fertilization of an egg cell by a sperm cell. They can become all of the cells of the human body, as well as the cells of the embryo and developing fetus.

At about four days into development, these totipotent cells specialize slightly, becoming pluripotent stem cells. [Read more…]

The Rise of Direct Cell Reprogramming

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There has been tremendous activity over the last decade in the development of stem cells therapeutics, which have relied on stem cell differentiation protocols, as well as techniques for direct cell reprogramming. Today, there are over 4,700 stem cell trials registered on ClinicalTrials.gov and publications have increased dramatically in recent years, demonstrating the rapidly growing interest of the scientific community.

However, for all its promise, stem cells are yet to deliver on this therapeutic potential, and this failure appears due to various technical challenges that still need to be overcome. [Read more…]

Cord Blood Banking Dynamics within India? Cesca Therapeutics’ Indian Subsidiary Expands

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The cord blood banking market is an interesting market, as its rate of growth has slowed over the past couple years. When the market is assessed by the number of cord blood units stored, cord tissue units banked, and number of units transplanted, there are regions that are experiencing growth and regions in decline. In particular, cord blood markets are experiencing strong growth within Asia, are relatively flat within North America, and are in decline within Europe. Additionally, cord blood banks within Europe have been some of the most proactive banks to expand into other areas of stem cell storage. [Read more…]

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