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Home » aging

Stem Cells and Aging: What’s the Connection?

December 28, 2020 By Cade Hildreth (CEO) Leave a Comment

stem cells and aging

Most people are interested in healthy aging, longevity and a long life span. These pursuits are intrinsic to optimizing the human experience.

In our quest for tools and technologies to support this aim, the scientific community has begun exploring the connection between stem cells and aging. Study after study is coming out delineating the paramount importance of stem cells in the aging process.

If you are into anti-aging research, stem cell therapy, and the intersection of these fields of research, then let’s dive in. [Read more…]

Filed Under: Stem Cells Tagged With: aging

AgeX Therapeutics Obtains $10 Million in Capital and Commences Operations

August 2, 2017 By Cade Hildreth (CEO) Leave a Comment

AgeX TherapeuticsAugust 02, 2017, ALAMEDA, Calif.–AgeX Therapeutics, Inc. (AgeX), a subsidiary of BioTime, Inc. (NYSE MKT: BTX), today reported that it has successfully raised $10 million in equity financing to fund its operations. Following the financing, BioTime continues to own about 87% of AgeX’s outstanding shares. The financing is expected to fund preclinical development at AgeX as well as building the company’s operational infrastructure. The financing may also lead to a registration and distribution of a to-be-determined percentag of the AgeX shares to BioTime shareholders, after which AgeX would trade as a public company. [Read more…]

Filed Under: Press Releases, Stem Cells Tagged With: aging, BioTime

BioViva Makes Controversial Announcement of First Gene Therapy Successful Against Human Aging

April 26, 2016 By Cade Hildreth (CEO) Leave a Comment

In massively exciting and controversial news, BioViva announced in a recent Science Magazine article:

In September 2015, then 44 year-old CEO of BioViva USA Inc. Elizabeth Parrish received two of her own company’s experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.

The treatment was originally intended to demonstrate the safety of the latest generation of the therapies.

But if early data is accurate, it is already the world’s first successful example of telomere lengthening via gene therapy in a human individual.

Gene therapy has been used to lengthen telomeres before in cultured cells and in mice, but never in a human patient.

Reactions to the BioViva Announcement of Human Telomere Lengthening via Gene Therapy

Of course, with every potential breakthrough comes both excitement and skepticism. It happened with the introduction of the internet, the Apple iPhone, self-driving cars, and nearly every other novel technology that has been integrated into society.

Indeed, this announcement by BioViva is about extremely early stage data on a sample size of one person.

Nonetheless, the importance of this announcement by BioViva is that it indicates further exploration should be done in the area of telomere lengthering via gene therapy approaches.

Interestingly, when I posted the BioViva announcement on Twitter, it got 30 reshares and 25 likes in approximately 24 hours, suggesting there is a lot of excitement surrounding the news.

Bioviva announces first gene therapy successful against human aging

The tweet also got extremely high levels of engagement with 2,612 people seeing the tweet in 24 hours and a nearly 5% engagement rate, as shown in the image below.

For reference:
  • The first column in the image below is the number of Impressions since the tweet was posted: 2,612 in 24 hours
  • The second column is the number of Engagements with the tweet: 124 clicks, retweets, follows, and likes in 24 hours
  • The third column is the Engagement Rate for the tweet, which is the total number of clicks, retweets, follows, and likes in 24 hours, divided by the total number of impressions: 4.7% of users engaged with the tweet during the first 24 hours it was posted.

High tweet engagement for Bioviva Telomore Lengthening Announcement on Twitter

Of course, the tweet also got this skeptical comment, which is fully merited as well.

I completely agree with this user that there are a great deal of unknowns and risks associated with this approach and its probability of success is limited by those factors.

Skepticism about Bioviva announcment

What is clear from this BioViva announcement is that there is growing progress with gene therapy approaches and increasing interest in aging-related issues. While progress with gene therapy for reversing human aging is is controversial and unknowable, this statement is fact.

To read the original Science Magazine article, visit: https://scienmag.com/first-gene-therapy-successful-against-human-aging/

What do you think about the announcement? Put you comments in the section below.

 

About BioInformant

BioInformant is the first and only market research firm to specialize exclusively in the stem cell industry. BioInformant research has been cited by major news outlets that include the Wall Street Journal, Nature Biotechnology, Medical Ethics, Xconomy, and Vogue Magazine. Serving Fortune 500 leaders that include GE Healthcare, Pfizer, and Goldman Sachs, BioInformant is your global leader in stem cell industry data.

Filed Under: Stem Cells Tagged With: aging, Bioviva, gene therapy, telomeres

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