BioInformant

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EONE-DIAGNOMICS Genome Center Partners with Cordlife to Expand Into East Asian Market

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CordLifeSEOUL, South Korea, Dec. 18, 2017  — Eone-Diagnomics Genome Center (EDGC), a Korean genetic analysis company, said today it will expand its business into East Asian market with Asia’s largest network of cord blood and cord lining banking service provider “Cordlife” as the company aims to expand its geographical presence in Asian genome market.

The company expects Cordlife, who operates its cord blood and cord lining banking business in numbers of Asian countries as a market leader, to be the best possible partner while the company is taking bold steps to grow in both scale and scope in Asian market.

EDGC will initially begin to service its Non-Invasive Prenatal Test (NIPT), named “Gen Screen,” to both the Philippines and Indonesia through Cordlife’s sales network within each country.

In particular, Indonesia has the second highest birth rate in the world after China. Making a move into such a country, the company is expected to see a definite steep growth in sales. [Read more…]

Magenta Therapeutics’ Expanded Stem Cell Product, MGTA-456, Engrafts in 100% of Patients

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– Data show rapid and durable engraftment with MGTA-456, an expanded cord blood stem cell product, in all 18 patients with hematologic malignancies across all conditioning regimens tested –
– MGTA-456 achieves clinical benefits of cord blood transplant –
– Clinically validated process to expand the numbers of CD34+ cells by >300 fold in single cord blood units significantly increases probability of identifying better HLA-matched stem cell donors for patients

Magenta Therapeutics - Cord Blood ExpansionDecember 11, 2017, CAMBRIDGE, Mass.–Magenta Therapeutics, a biotechnology company developing therapeutics to improve and extend the use of curative bone marrow transplant for more patients, today reported Phase 2 clinical data from its MGTA-456 hematopoietic stem cell (HSC) expansion program at the 59th annual meeting of the American Society of Hematology (ASH) in Atlanta, Ga. MGTA-456 is a single umbilical cord blood unit expanded with an aryl hydrocarbon receptor (AHR) antagonist. It is currently being studied in adult and pediatric patients with hematologic malignancies.

[Read more…]

ORIG3N, World’s Largest Blood Cell Repository for iPS Cell Production

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ORIG3N LogoORIG3N, an innovative biotech company that creating the world’s largest blood cell repository for induced pluripotent stem cell (iPS cell) production. I first met James Lovgren, Chief Business Officer of ORIG3N, at the World Stem Cell Summit in 2015. As a result of that connection and conversation, I am pleased to share this interview with him below. [Read more…]

Gladstone Institutes Initiates Research Collaboration With Eli Lilly for Neurodegenerative Diseases

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Study will use innovative technology to focus on neurodegenerative diseases

Gladstone and Eli Lilly
Steve Finkbeiner, M.D., Ph.D., Senior Investigator, Gladstone Institute of Neurological Disease

SAN FRANCISCO, December 7, 2017 (Newswire.com) – The Gladstone Institutes announced today a new research collaboration with Eli Lilly and Company focused on neurodegenerative diseases. This multi-year, milestone-driven project will be based on a combination of innovative technologies developed at Gladstone by Steve Finkbeiner, M.D., Ph.D. His laboratory will work closely with Lilly during this collaboration.

“This collaboration has high potential to open new avenues towards effective therapies for neurodegenerative diseases,” said Gladstone President R. Sanders Williams, M.D. “Both organizations are committed to meeting this major unmet need.”

Key to the project is a robotic microscope system developed in Finkbeiner’s laboratory with funds from Gladstone, the Taube/Koret Center for Neurodegenerative Disease Research, and the ALS Association. This fully automated platform allows scientists to track thousands of individual cells for days or weeks at a time, and follow discrete cellular functions.

When coupled with neurons generated from induced pluripotent stem cells collected from patients with neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and ALS, this microscope becomes a powerful tool to study the cells and their responses to disease and treatments. [Read more…]

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