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Japanese government-certified clinic applies ISCT-compliant flow-cytometry release criteria to patient-specific adipose-derived stem cell cultures, serving patients from approximately 20 countries
OSAKA, Japan — June 2026 — Cell Grand Clinic (CGC), a Japanese government-certified regenerative medicine clinic, has been named Top Regenerative Medicine Solution Provider in APAC 2026 by Healthcare Business Review APAC, recognition that places CGC among the region’s top 10 regenerative medicine providers. The clinic operates 13 Ministry of Health, Labour and Welfare (MHLW)-certified treatment plans — among the highest concentrations in Osaka — using autologous adipose-derived stem cell (ADSC) therapy for conditions spanning knee osteoarthritis, type 1 and type 2 diabetes, arteriosclerosis, age-related decline and whole-body anti-aging (frailty), and dermatologic and androgenetic applications, serving patients from approximately 20 countries. A 14th plan, autologous ADSC therapy for Alzheimer’s disease, is under MHLW review and is scheduled to launch in July 2026.
What distinguishes CGC within the industry is its manufacturing discipline. Every culture is patient-specific, with no batch pooling across donors. Cells are expanded to a passage-3 (P3) culture stop and released against ISCT-compliant flow-cytometry criteria — CD73, CD90 and CD105 near-100 percent positive — with post-thaw viability above 95 percent. During the seven-week culture window, the clinic administers same-day symptomatic therapy (exosomes or PRP) at the time of adipose harvest, removing the interval that conventional protocols leave between cell collection and administration.
“Continuity of physician oversight is the operational principle of this clinic,” said Dr. Yuichi Wakabayashi, MD, PhD, founder of Cell Grand Clinic and an American Board of Regenerative Medicine (ABRM)-certified specialist. “The same physician designs the protocol, performs the harvest, supervises culture, administers the cells and tracks outcomes.”
Dr. Wakabayashi was previously a research fellow at the U.S. National Institutes of Health (NIH), where he authored peer-reviewed work on Alzheimer’s disease pathology, and co-led PET radioligand development with Pfizer Inc. He has performed more than 3,000 ADSC treatments and lectures in regenerative medicine at Kindai University School of Medicine.
The clinic’s standardization and single-physician model serve an international patient base from approximately 20 countries, with English-language consultations directly from the founding physician. CGC is a member of Medical Excellence JAPAN (MEJ) and has been featured in The Wall Street Journal and Healthcare Business Review APAC.
Reported clinical outcomes vary by individual and are not guaranteed. CGC does not present its therapies as cures.
About Cell Grand Clinic
Cell Grand Clinic (CGC) is a regenerative medicine clinic in central Osaka, Japan, founded in 2025 by Dr. Yuichi Wakabayashi. The clinic specializes in autologous adipose-derived stem cell (ADSC) therapy and operates 13 MHLW-certified treatment plans across orthopedic, metabolic, cardiovascular, dermatologic and anti-aging applications. CGC serves international patients from approximately 20 countries with English-language consultations directly from the founding physician. Learn more at cellgrandclinic.com/en.
Related Resources
- Knee osteoarthritis — https://cellgrandclinic.com/column_en/stem-cell-therapy-for-knees-japan/
- Type 1 and type 2 diabetes — https://cellgrandclinic.com/column_en/stem-cell-therapy-diabetes-regenerative-medicine/
- Arteriosclerosis — https://cellgrandclinic.com/column_en/stem-cell-therapy-for-atherosclerosis-stroke-and-myocardial-infarction/
- Anti-aging and longevity (frailty) — https://cellgrandclinic.com/column_en/stem-cell-therapy-back-aging-longevity-anti-aging-regenerative-medicine-en/
- Skin rejuvenation — https://cellgrandclinic.com/column_en/stem-cell-skin-rejuvenation/
- Hair loss (AGA / FAGA) — https://cellgrandclinic.com/column_en/stem-cell-therapy-hair-loss-aga-faga/
Media Contact
Cell Grand Clinic Nishi-Shinsaibashi 2-3-2, Midosuji Minami Bldg. 4F, Chuo-ku, Osaka 542-0086, Japan Email: [email protected] · Phone: +81-6-6212-5960 Website: https://cellgrandclinic.com/en/
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