Blog | BioInformant

Dr. Askenase on the Role of MSC-Derived Exosomes in Healing the Injured Spinal Cord

February 24, 2025 By Cade Hildreth, Founder & President Leave a Comment

This interview features Dr. Philip Askenase, MD, a Professor of Medicine and Pathology at Yale University School of Medicine. A leading expert in the effector properties of exosomes, Dr. Askenase is now delving into the regenerative potential of mesenchymal stem cell (MSC)-derived exosomes.

His latest, as-yet-unpublished research focuses on using MSC-derived exosomes to promote healing in injured spinal cords in rats. In our conversation, we examine the expanding significance of MSC-derived exosomes, their unique advantages, and diverse applications. We also discuss the market opportunities for stem cell exosomes and the companies driving innovation in this emerging field.

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Stem Cell Treatment For Knees

February 22, 2025 By Cade Hildreth, Founder & President 1 Comment

Stem cell treatment for knees can be very effective. The process uses your own stem cells to heal your body. This innovative treatment option offers various benefits. It is safe and highly effective without risk of side effects or rejection. It is important to know what to expect. For those who are considering it, doctors will provide key information you need.

Stem Cell Treatment For Knees

Stem cells are a building block in the body. These cells are very valuable. They are unlike other cells in the body. Most cells have the ability to do one job.

What Are Stem Cells?

Stem cells differ, because they can become any other cell in the body. They can also replicate themselves to create new stem cells. As a result, they can help fix problem areas. Stem cell treatment is a form of self-healing. [Read more…]

New Frontiers in Gene-Editing and Stem Cell Innovation – Interview with Dr. Chen-Tsai of Applied StemCell

February 20, 2025 By Cade Hildreth, Founder & President 3 Comments

I had the honor of interviewing Dr. Ruby Yanru Chen-Tsai, Chief Scientific Officer and Co-founder of Applied StemCell Inc. (ASC), a fast growing biotechnology company in Milpitas, California. Specializing in gene-editing technologies and stem cell innovation, ASC offers an optimized series of tools for basic research study, drug discovery, bio-processing, bio-production and preclinical applications.

In this fascinating interview, we discuss Dr. Yanru Chen-Tsai’s impressive background, ASC’s unique product portfolio, its TARGATT™ gene editing technology, and the company’s future trajectory. [Read more…]

Cellistic Launches Allo Chassis™: Ready-to-use, immune-cloaked iPSC Cell Lines facilitating cost-effective cell therapy development

February 17, 2025 By Cade Hildreth, Founder & President Leave a Comment

MONT-SAINT-GUIBERT, Belgium — Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of its Allo Chassis™—ready-to-use, immune-cloaked iPSC cell lines derived from CD34+ and CD4+ T-cell primary cells. These innovative cell lines represent a substantial leap forward in cell line development, effectively reducing both timelines and costs. Leveraging Cellistic’s extensive expertise in iPSCs, including in the development of T-cell based treatments, the Allo Chassis™ cell lines set a new standard in the cell therapy market with their unprecedented technology, developed in accordance with current Good Manufacturing Practice (cGMP) standards. [Read more…]

Academic and Medical CDMOs Serving the Cell Therapy Industry

February 16, 2025 By Cade Hildreth, Founder & President Leave a Comment

In addition to commercial cell therapy CDMOs, there are other industry players that support the cell therapy industry, including academic and medical CDMOs. While these groups do contribute to the cell therapy CDMO market, their manufacturing capabilities are limited in scale and best suited to small, early-stage clinical trials. [Read more…]