In this article, Dr. Daniel Kota provides a mesenchymal stem cell review and explores the future of MSC therapy. Mesenchymal stem cells (MSCs) are multipotent cells that prefer to differentiate into cells of the musculoskeletal system, such as bone, cartilage, muscle and fat cells. However, MSCs can also be induced to become other cell types, as well as exert therapeutic effects by honing to sites of repair and secreting therapeutic agents.
Is Storing Your Immune Cells Really Worth It?
While cryopreserving cell tissue, stem cells and other blood products is nothing novel, the emerging field of immune cell banking certainly is. Immune cells are all the cells that make up your immune system, including T-cells, B-cells, NK cells, neutrophils cells, monocytes, dendritic cells, etc. They are your body’s first line of defense against infection and disease. New immunotherapies, such as CAR T-cell, CAR NK and dendritic cell therapies, are currently being developed to leverage those cells and offer new, experimental treatment options for cancer patients.
Storing immune cells may be a fairly new concept, but the potential benefits of storing immune cells have made forward-thinking, health-conscious individuals take notice. [Read more…]
What Is the Best Lyme Disease Treatment?
Did you know that experts estimate that 300,000 people may get Lyme disease each year in the USA?
This disease if it remains unchecked, can lead to more painful ailments including symptoms resembling arthritis.
If you are a nature lover and love to go trekking but are worried about Lymes disease what treatments are available? Or you or a loved one may currently be sick with Lymes disease and would like to research treatment options. What is the best Lyme disease treatment? [Read more…]
Development of iPSC-derived Disease Models
Human induced pluripotent stem cell (iPSC)-based models are a valuable resource for studying disease mechanisms in vitro at the cellular level[1], screening potential new therapeutics[2], and investigating the propensity and mechanism for the development of toxic side effects caused by a drug treatment[3]. Such iPSC-based models enable research to be performed under defined experimental conditions and in a reproducible manner. [Read more…]
MSCs as Essential Raw Materials for Regenerative Medicine Products
MSCs are essential raw materials for many regenerative medicine products, including cell-based therapies, engineered tissues, cosmeceutical preparations, exosome products, and cultured meat. As of today, ClinicalTrials.gov lists at least 2,232 registered clinical trials involving MSCs, targeting a variety of indications ranging from graft vs. host disease (GvHD) to macular degeneration to osteoarthritis. Although ten MSC-based therapeutics have been approved for marketing in other parts of the world, the U.S. FDA is yet to approve an MSC product. Nonetheless, given their therapeutic potential for treating many indications and usage across a variety of applications, researchers believe that MSCs will support many important regenerative medicine advances. [Read more…]
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