Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into a variety of cell types, including bone, cartilage, muscle and fat cells, among other cell types. MSCs are a leading type of adult stem cell being investigated for therapeutic applications, because they have the potential to treat a range of acute and degenerative diseases. [Read more…]
What Is An Allogeneic Stem Cell Transplant?
People struggling with cancer may undergo an allogeneic stem cell transplant, which involves replacing unhealthy stem cells with new ones. Because using a patient’s own stem cell can be unpredictable, many patients use donated bone marrow stem cells for this procedure. If successful, the procedure can help fight off cancer and leukemia. Find out what allogeneic stem cell transplant is, including how it works, as well as the risks and benefits involved with the procedure. [Read more…]
Can Asthma Treatment Be Achieved Through Stem Cell Therapy?
Progress with regenerative medicine is supporting the development of a new type of asthma treatment that has the potential to reduce asthma attacks and repair lung damage.
In this article:
Direct Cell Reprogramming: What Is It and How Does It Work?
Direct cell reprogramming is the in vitro (laboratory) or in vivo (in the body) reprogramming of somatic cells into other cell types without the need for an intermediate pluripotent state. Another term for direct cell reprogramming is transdifferentiation, which is the direct conversion of one differentiated cell type into another.
There has been tremendous activity over the last decade in the development of stem cells therapeutics, which have relied on stem cell differentiation protocols, as well as techniques for direct cell reprogramming. Today, there are over 7,149+ stem cell trials registered on ClinicalTrials.gov and stem cell publications have increased dramatically in recent years, recently surpassing 500,000+ on PubMed.gov.
However, for all their promise, stem cells are yet to deliver on this therapeutic potential, and this failure appears due to various technical challenges that still need to be overcome. [Read more…]
Therapeutic Applications of Umbilical Cord Blood & Tissue Proliferate in 2026
Cancer treatment using very high-dose chemotherapy or radiation therapy often results in severe injury to a patient’s blood-forming cells, called their hematopoietic (“blood formation”) system. Therefore, radiation therapy is soon followed by hematopoietic stem cell transplantation (HSCT), which is a method of reconstructing a patient’s blood system that has been destroyed by cancer treatment. Cord blood can also be used as a source of stem cells for hematopoietic stem cell transplantation (HSCT), providing an important alternative to the traditional options of peripheral blood and bone marrow transplant. Importantly, bone marrow and peripheral blood require full tissue matching for use in HSCT, while umbilical cord blood only requires partial matching. [Read more…]
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