Market forces driving growth of the exosome have been expanding over the past two years, with increasing investment flowing into the space, merger and acquisition (M&A) activity accelerating, and new therapeutics entering various stages of development. Exosomes are defined as small vesicles ranging from 30-100nm in size that are found in nearly all eukaryotic fluids and facilitate a range of important cellular functions. They transfer DNA, RNA, and proteins to other cells, thereby altering the function of the targeted cells. They are made in some form by all species, including bacteria that produce analogous outer membrane vesicles (OMC). [Read more…]
denovoMATRIX Introduces Ready-to-use, Chemically Defined Coated Cell Cultureware for Serum-free hMSC Expansion
August 22, 2019, Dresden, Germany — Due to their high accessibility and extensive beneficial properties, human Mesenchymal Stem Cells (hMSC) offer exciting promises in a plethora of applications in regenerative medicine, particularly in cell-based therapies. The major challenge of hMSC-based therapy is the large-scale expansion of cells in order to achieve the cell numbers necessary for therapeutic treatment. [Read more…]
Nucleus Biologics acquires Primorigen Biosciences, gains proprietary, high yield, recombinant protein platform
SAN DIEGO, Aug. 6, 2019 — Nucleus Biologics, a leader in precision cell culture, is pleased to announce the acquisition of Primorigen Biosciences, Inc. The addition of Primorigen’s Vitronectin XF™ and platform recombinant protein production technology will play a huge role in Nucleus’ strategy of offering traceable, reproducible and xeno-free (XF) cell culture ecosystems for the cell and gene therapy space. [Read more…]
GenCure announces breakthrough first run of 80-liter bioreactor
Biomanufacturing CDMO among first to harvest adult stem cells at large scale
SAN ANTONIO, Texas – In a breakthrough for the regenerative medicine industry, GenCure announced today that its biomanufacturing services team has successfully completed production runs expanding and harvesting human mesenchymal stem cells (hMSCs) in an 80-liter bioreactor. GenCure, a subsidiary of BioBridge Global (BBG), announced a major expansion of its biomanufacturing facilities in February of this year. [Read more…]
Biological Industries USA Adds Strategic Offering of Small Molecules to its Stem Cell Portfolio
August 8, 2019 — CROMWELL, Conn. — Biological Industries USA (BI-USA), a division of Biological Industries Beit Haemek Israel (BI), and provider of cell culture tools for translational research, today announced the addition and sale of small molecules for stem cell applications; specifically for enhancing research in diabetes, neural disorders, and cardiovascular disease.
Small molecules can be used to modulate biological signals for a multitude of applications, including cellular reprogramming, stem cell self-renewal, and the differentiation of stem cells into specific lineages, altogether advancing the rapidly evolving field of translational cell therapy. [Read more…]
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