Human induced pluripotent stem cell (iPSC) technology offers the benefits of a cell line, coupled with the advantage of using human primary cells. Applied StemCell (ASC) has developed a panel of iPSC lines for neurotoxicity assays and disease modeling applications.
These cell lines include:
- Control lines
- Patient-specific lines
- Lineage-specific knock-in reporters
- Isogenic controls of single and double knock-outs
ASC has also established scalable protocols for generating differentiated cells in an assay-ready format.
Upcoming Webinar
In an upcoming webinar scheduled for Wednesday, May 31st, 2017, ASC will describe the utility of these lines for neurotoxicity assays, including assays to determine the specificity of different neural cell types for a small range of chemicals and drugs from the Tox21 library, as well as for neuroprotective assays with dopaminergic neurons.
Webinar Details:
Date: Wed, May 31, 2017
Time: 11:00 AM – 12:30 PM PDT
Length: Total 45 minClick to Register
Additional iPSC-based Toolkits and Solutions
Applied StemCell is now offering comprehensive iPSC-based toolkits & solutions for all your neurological research and discoveries:
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- Two control “master” iPSC lines: reprogrammed from male and female cord blood; karyotype normal, integration-free and footprint-free
Click here for more details. - Two panels of Isogenic neural stem cells, neurons & glial cells differentiated from each control iPSC line
Click here for more details. - Panels of Genome Engineered iPSC lines and differentiated lineages available from both control “master” lines:
Click here for more details. - Associated media and reagents
- Two control “master” iPSC lines: reprogrammed from male and female cord blood; karyotype normal, integration-free and footprint-free
Also, available are fully customizable stem cell services, including:
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- iPSC generation from patient samples
- iPSC genome editing
- iPSC differentiation: neural lineage, cardiomyocytes, hepatocytes and more
- Stem cell characterization: pluripotency markers, teratoma, karyotyping
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