Dental pulp is the soft living tissue inside a tooth that contains mesenchymal stem cells (MSCs). The ideal time to harvest dental stem cells is when children lose their deciduous (baby) teeth, either through natural loss or extraction.
An important way to gauge innovation and progress within the dental stem cell market is to consider trend rate data for scientific publications over a trailing ten-year period.
Analysis of Scientific Publication Data
PubMed is a service of the U.S. National Library of Medicine and the National Institutes of Health (NIH) that contains citations from MEDLINE and a collection of other life science journals.
The data presented below was generated using the PubMed database, because it is the largest, most comprehensive, and most up-to-date resource aggregating scientific publications worldwide.
It is also the most versatile tool for screening by multiple criteria.
For purposes of this analysis, the following search terms were searched simultaneously:
- Teeth + “Stem Cells”
- Tooth + “Stem Cells”
- Dental + “Stem Cells”
- “Dental Follicle Progenitors Cells”
- “Stem Cells” + “Apical Papilla”
- “Periodontal Ligament Stem Cells”
- “Stem Cells” + SHED
For those unfamiliar with dental stem cell language, SHED is an acronym for “stem cells from human exfoliated deciduous teeth.”
The goal of these search terms was to:
- Capture terms and synonyms descriptive of dental stem cells
- Capture results in which the word order may vary – For example, searching for (“Dental” + “Stem Cells”) allows us to capture phrases that include: “Dental Pulp Stem Cells,” “Dental Stem Cells,” “Stem Cells from Dental Pulp,” etc.
- Capture long-tail searches, in which our terms of interest appear within longer, contextual descriptions
While these terms listed above likely do not capture every single result in the scientific literature pertaining to dental stem cells, they do capture the clear majority of them, thereby revealing valuable trend data.
*Note: Full-year 2017 figures are estimates based on data from Jan. 1 – Sept. 30, 2017.
Clearly, scientific publication data reveals growing interest in dental stem cells over the past ten years.