Dental stem cell companies are companies that preserve the valuable cells contained with dental structures. While stem cells from teeth have not yet been approved for therapeutic use in humans, there is great potential for their future use within regenerative medicine applications.
In this article:
Dental Stem Cell Companies
Simply put, dental stem cell companies collect and preserve cells from teeth. Dental pulp is the soft living tissue inside a tooth that contains adult stem cells. The ideal time to harvest dental stem cells is when children lose their baby teeth through natural loss or extraction by a dentist.
Although dental pulp gets the most attention, there are stem cell and progenitor cells present in other oral structures as well.
Storing Stem Cells from Teeth
Five different types of dental stem cells have been discovered, which include:
- Dental pulp stem cells (DPSCs) – These are stem cells isolated from the dental pulp of human third molars
- Dental follicle progenitor cells (DFPCs) – The dental follicle contains periodontal progenitor cells
- Stem cells from apical papilla (SCAP) – Mesenchymal stem cells (MSCs) are present in the apical papilla of permanent immature teeth
- Periodontal ligament stem cells (PDLSCs) – These cells are present in the periodontal tissue that surround the teeth
- Stem cells from human exfoliated deciduous teeth (SHED) – These cells are present within the dental pulp tissue of deciduous (baby) teeth
Stem Cell Banking Companies with Dental Storage
The following are the companies offering dental stem cells storage as part of a diversified stem cell storage approach. Each of these companies was created as a cord blood bank to collect and store the blood present in a newborn’s umbilical cord, because this blood contains a rich population of stem cells.
Similar to cord blood banking, dental stem cell banking involves stem cell collection, processing, and long-term storage. Therefore, it is an excellent service addition for many cord blood banks, including:
- Future Health Biobank (Nottingham, UK)
- GeneCell International (Miami, FL)
- VAULT SC Inc (Palm Coast, FL)
- Transcell Biologics Pvt Ltd (Hyderabad, India)
- ReeLabs (Mumbai, India)
- Precious Cells Group (PCG) (London, UK) – Unfortunately, PCG went out of business in March 2018
Tooth Stem Cell Companies
In addition, specialty companies also exist that focus exclusively on dental stem cell storage.
The major players in this area include:
- BioEden (Austin, TX)
- Bank A Tooth, a Singapore incorporated company specializing in dental stem cell banking, is a product of Prolife Biobank (Singapore)
- DentCell (Naucalpan, Mexico)
- National Dental Pulp Laboratory (Marlborough, MA)
- Stemade (Mumbai, India)
- Stemodontics (USA)
- StemSave (New York, NY)
- “Store-a-Tooth” run by Provia Laboratories, LLC (Littleton, MA)
- Tooth Bank (Brownsburg, IN)
More Dental Companies for Storage
While there are many other small providers of tooth stem cell storage, the companies listed above account for more than 80% of the total market share, according to estimates by BioInformant.
Leading Dental Stem Cell Companies
Below, six leading dental stem cell companies are profiled and their storage services explained.
BioEden began offering tooth stem cell storage as early as 2006, making it one of the earliest known providers of dental stem cell storage. Read our interview with Tony Veverka, Chief Group Executive of BioEden.
Precious Cells Group (PCG)
Precious Cells Group (PCG) got into dental stem cell banking by entering into a strategic alliance to provide processing, laboratory and regulatory undertakings on behalf of Bioeden in the U.K.
Unfortunately, PCG went out of business in March 2018 and no longer offers dental stem cell storage services.
National Dental Pulp Laboratory
The National Dental Pulp Laboratory launched in 2007.
Originally, the company was formed in the early 1970’s as a cryogenic laboratory specializing in fertility work. In the mid 1990]s, it began preserving stem cells from umbilical cord blood, and today, it also offers storage for the stem cells found in teeth.
According to Stemade, it is the first and largest private dental stem cell storage company in India. The company has also served areas of Asia since 2013 . Stemade licenses their dental storage technology from Institut Clinident Biopharma, which it describes as “offering a technical solution to the collection and preservation of the dental pulp, rich in adult stem cells”. The Institut Clinident Biopharma also licenses its technology to European companies as well.
Stemodontics™ is a dental stem cell storage group that partners with oral and maxillofacial surgeons. After completing an online enrollment process, Stemodontics’ lab sends a collection kit to your surgeon for an upcoming procedure. Once a tooth has been removed, it is stored and shipped to Stemodontic’s lab overnight for immediate processing and storage. When you’re ready to utilize your stem cell sample, you contact Stemodontics and your sample gets shipped to your designated healthcare provider.
There is also ReeLabs, a major enterprise for stem cell storage in India, banking cells from over ten human sources. To learn more about ReeLabs, read our interview with Dr. Abhijit Bopardikar, Director.
Clearly, the regions that are currently most active in offering dental stem cell storage are the United States, India, and the United Kingdom, respectively.
If you found this blog valuable, subscribe to BioInformant’s stem cell industry updates.
What other questions do you have regarding tooth stem cells and dental stem cell companies? Mention them in the comments below.
 Us.bioeden.com, (1963). About BioEden Inc | Stem cells | Tooth stem cell storage bank. [online] Available at: http://us.bioeden.com/about/ [Accessed 4 Nov. 2014].
 Ndpl.net,. ‘National Dental Pulp Laboratory | Preserving Dental Stem Cells’. N.p., 2015. Web. 19 Sept. 2015.
 Stemade.com,. “Stemade – India’s First & Largest Dental Stem Cell Bank”. N.p., 2015. Web. 01 Dec. 2015.
 Biospectrumasia.com,. “Asia’s First Dental Stem Cell Bank Is Here”. N.p., 2015. Web. 02 Dec. 2015.
 Stemade.com/about/partners,. “Stemade Partner”. N.p., 2015. Web. 01 Dec. 2015.
 Reelabs.com,. “Stem Cell Banking & Therapy In India | Reelabs”. N.p., 2015. Web. 18 Dec. 2015.