Dental stem cell companies are companies that preserve the valuable cells contained with dental structures. While stem cells from teeth have not yet been approved for therapeutic use in humans, there is great potential for their future use within regenerative medicine applications.
In this article:
Dental Stem Cell Companies
Simply put, dental stem cell companies collect and preserve cells from teeth. Dental pulp is the soft living tissue inside a tooth that contains adult stem cells. The ideal time to harvest dental stem cells is when children lose their baby teeth through natural loss or extraction by a dentist.
Although dental pulp gets the most attention, there are stem cell and progenitor cells present in other oral structures as well.
Storing Stem Cells from Teeth
Five different types of dental stem cells have been discovered, which include:
- Dental pulp stem cells (DPSCs) – These are stem cells isolated from the dental pulp of human third molars
- Dental follicle progenitor cells (DFPCs) – The dental follicle contains periodontal progenitor cells
- Stem cells from apical papilla (SCAP) – Mesenchymal stem cells (MSCs) are present in the apical papilla of permanent immature teeth
- Periodontal ligament stem cells (PDLSCs) – These cells are present in the periodontal tissue that surround the teeth
- Stem cells from human exfoliated deciduous teeth (SHED) – These cells are present within the dental pulp tissue of deciduous (baby) teeth
Stem Cell Banking Companies with Dental Storage
The following are the companies offering dental stem cells storage as part of a diversified stem cell storage approach. Each of these companies was created as a cord blood bank to collect and store the blood present in a newborn’s umbilical cord, because this blood contains a rich population of stem cells.
Similar to cord blood banking, dental stem cell banking involves stem cell collection, processing, and long-term storage. Therefore, it is an excellent service addition for many cord blood banks, including:
- Future Health Biobank (Nottingham, UK)
- GeneCell International (Miami, FL)
- VAULT SC Inc (Palm Coast, FL)
- Transcell Biologics Pvt Ltd (Hyderabad, India)
- ReeLabs (Mumbai, India)
- Precious Cells Group (PCG) (London, UK) – Unfortunately, PCG went out of business in March 2018
Tooth Stem Cell Companies
In addition, specialty companies also exist that focus exclusively on dental stem cell storage.
The major players in this area include:
- BioEden (Austin, TX)
- Bank A Tooth, a Singapore incorporated company specializing in dental stem cell banking, is a product of Prolife Biobank (Singapore)
- DentCell (Naucalpan, Mexico)
- National Dental Pulp Laboratory (Marlborough, MA)
- Stemade (Mumbai, India)
- Stemodontics (USA)
- StemSave (New York, NY)
- “Store-a-Tooth” run by Provia Laboratories, LLC (Littleton, MA)
- Tooth Bank (Brownsburg, IN)
More Dental Companies for Storage
While there are many other small providers of tooth stem cell storage, the companies listed above account for more than 80% of the total market share, according to estimates by BioInformant.
Leading Dental Stem Cell Companies
Below, six leading dental stem cell companies are profiled and their storage services explained.
BioEden
BioEden began offering tooth stem cell storage as early as 2006[1], making it one of the earliest known providers of dental stem cell storage. Read our interview with Tony Veverka, Chief Group Executive of BioEden.
Precious Cells Group (PCG)
Precious Cells Group (PCG) got into dental stem cell banking by entering into a strategic alliance to provide processing, laboratory and regulatory undertakings on behalf of Bioeden in the U.K.
Unfortunately, PCG went out of business in March 2018 and no longer offers dental stem cell storage services.
National Dental Pulp Laboratory
The National Dental Pulp Laboratory launched in 2007[2].
Originally, the company was formed in the early 1970’s as a cryogenic laboratory specializing in fertility work. In the mid 1990]s, it began preserving stem cells from umbilical cord blood, and today, it also offers storage for the stem cells found in teeth.
Stemade
According to Stemade, it is the first and largest private dental stem cell storage company in India.[3] The company has also served areas of Asia since 2013 [4]. Stemade licenses their dental storage technology from Institut Clinident Biopharma, which it describes as “offering a technical solution to the collection and preservation of the dental pulp, rich in adult stem cells”[5]. The Institut Clinident Biopharma also licenses its technology to European companies as well.
Stemodontics
Stemodontics™ is a dental stem cell storage group that partners with oral and maxillofacial surgeons. After completing an online enrollment process, Stemodontics’ lab sends a collection kit to your surgeon for an upcoming procedure. Once a tooth has been removed, it is stored and shipped to Stemodontic’s lab overnight for immediate processing and storage. When you’re ready to utilize your stem cell sample, you contact Stemodontics and your sample gets shipped to your designated healthcare provider.
ReeLabs
There is also ReeLabs[6], a major enterprise for stem cell storage in India, banking cells from over ten human sources. To learn more about ReeLabs, read our interview with Dr. Abhijit Bopardikar, Director.
Clearly, the regions that are currently most active in offering dental stem cell storage are the United States, India, and the United Kingdom, respectively.
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What other questions do you have regarding tooth stem cells and dental stem cell companies? Mention them in the comments below.
Footnotes
[1] Us.bioeden.com, (1963). About BioEden Inc | Stem cells | Tooth stem cell storage bank. [online] Available at: http://us.bioeden.com/about/ [Accessed 4 Nov. 2014].
[2] Ndpl.net,. ‘National Dental Pulp Laboratory | Preserving Dental Stem Cells’. N.p., 2015. Web. 19 Sept. 2015.
[3] Stemade.com,. “Stemade – India’s First & Largest Dental Stem Cell Bank”. N.p., 2015. Web. 01 Dec. 2015.
[4] Biospectrumasia.com,. “Asia’s First Dental Stem Cell Bank Is Here”. N.p., 2015. Web. 02 Dec. 2015.
[5] Stemade.com/about/partners,. “Stemade Partner”. N.p., 2015. Web. 01 Dec. 2015.
[6] Reelabs.com,. “Stem Cell Banking & Therapy In India | Reelabs”. N.p., 2015. Web. 18 Dec. 2015.
The National Dental Pulp Laboratory in Marlborough MA. should also be on that list. We are the oldest, we started back in the mid 2000’s, our parent company New England Cryogenic Center has been in business since the 70’s as well as New England Cord Blood Bank.
Travis, thank you for this information. This is an important dental storage company to include. The post has been updated!
Transcell Biologics Pvt. Ltd is a complete stem cell bank operating from Hyderabad, India. The company sources therapeutic stem cells from clinically validated sources like Cord, Tooth, Fat and Bone marrow, stores in the repository for any kind of required applications
Dr. Dravida – Thank you for this important addition. Transcell Biologics Pvt. Ltd has now been added to this post. Please keep us updated as you add new stem cell market segments to your services.
It is important to note that many of the above only cryogenically freeze the tooth without expanding cells.How do you know there will be useable cells 30 years from now?All banks are NOT equal! In addition, how many process under a cGMP lab protocol? This will be important as more stringent processes are implemented, and the industry matures.
Hi Cade,
I would be very interested in getting more details on the dental Bank in Australia for my patients.
Regards,
Dr Saurav Gupta
Dr. Gupta – We will do our best to keep you updated about dental stem cell banking in Australia and worldwide. Best, Cade
Thankyou Cade
Hello Cade! We are based in Mexico City. Our commercial enterprise is Store a Cell. We´ve been 6 years on the market. We started with Dental pulp and now we expanded the license and store adipose tissue, umbilical cord, placenta, bone marrow. For more info www. storeacell.com or follow us on facebook Storeacell
This list is outdated. Provia labs bought Vault.
Mothercell Biosciences, The Biggest Dental stencil bank in the world was established on 23rd Aug 2016 and the laboratory was constructed in 33,000 SFT state of the art laboratory. Mothercell is the most advanced laboratory in the World with the most advanced and high end equipment. Mothercell is a QBD ( quality by Design ) structure as the infrastructure was built for Stemcell bank and hence no compromise in providing the best amenities and its a totally fire proof building. For more details and images pls do visit http://www.mothercell.com and Mothercell should be in the top among the best Dental Stemcell banking companies in the world.