CAMBRIDGE, Mass., Nov. 12, 2021 — Editas Medicine, Inc. (Nasdaq: EDIT), a genome editing company, announced preclinical data on its progress in the development of novel engineered induced pluripotent stem cell (iPSC)-derived natural killer cells (iNKs) for the treatment of cancer. In the presentation, the Company showed a new method to achieve high-levels of expression of CD16 and Interleukin-15 (IL-15) in iNK cells by using the Company’s proprietary CRISPR/Cas12a-mediated SLEEK (SeLection by Essential-gene Exon Knock-in) technology to simultaneously knock-in both functional genes. The modifications resulted in improved serial tumor killing and dramatically increased NK cell persistence. [Read more…]
Saint-Gobain Life Sciences and denovoMATRIX Announce Collaboration to Optimize New Product Development
DRESDEN, Germany, 9 November, 2021 / BioInformant / — denovoMATRIX GmbH and Saint-Gobain Life Sciences have entered into a Master Service Agreement focused on optimizing the performance of new products in development for adherent cell culture and harvest for autologous therapies. The relationship will further explore the synergy of consumable products from both parties and their positive effects for the therapeutic market. [Read more…]
Ncardia Secures $60+ Million to Enhance and Expand Leading iPSC Offerings
Ncardia forms strategic partnership with Kiniciti to build GMP capabilities to support iPSC cell therapy platforms and human cell-based in vitro discovery services
November 16, 2021, GOSSELIES, Belgium & NEW YORK — Ncardia, a leader in developing stem cell-based solutions for drug discovery and cell therapy, announced that it has secured more than $60 million in capital through a strategic partnership with Kiniciti, a U.S.-based investment platform focused on strengthening the cell and gene therapy ecosystem worldwide. [Read more…]
Shoreline Biosciences Announces $140M Financing To Advance Pipeline of iPSC-based Cell Immunotherapies
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Shoreline Biosciences Announces $140M Financing To Advance Its Growing Pipeline Of Next Generation Cell Immunotherapies
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Financing accelerates the growth of Shoreline’s pipeline of iPSC-based cell immunotherapies for the treatment of seriously ill patients and enables the buildout of smart manufacturing capabilities.
The State of CAR-T Cell Therapies in 2021
Scientific progress within the field of cancer immunotherapy has led to five CAR-T cell therapy approvals: Kymriah (tisagenlecleucel), Yescarta (axicabtagene ciloleucel), Tecartus (brexucabtagene autoleucel), Breyanzi (lisocabtagene maraleucel), and Abecma (idecabtagene vicleucel). Additionally, JW Therapeutics has announced NMPA approval of Relmacabtagene Autoleucel Injection in China. This is the first CAR-T product independently developed in China and approved as a Category 1 biologics product, as well as the sixth approved CAR-T product globally. [Read more…]
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