Stem cell companies have been rapidly populating on a global basis. Today, there surging numbers of market competitors developing stem cell therapeutics for use in humans. Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into mature cell types.
Stem cell research has been going on for over 50 years, because stem cells have a unique ability to divide and replicate repeatedly. In addition, their unspecialized nature allows them to become a wide variety of tissue types, which gives them enormous potential for use in regenerative medicine.
Stem cell companies are exploring clinical applications ranging from diabetes to multiple sclerosis to macular degeneration.
List of Stem Cell Companies
Below is an ever-growing list of market competitors who are involved with the development of stem cell therapeutics.
| Company | Website | Location | Country | Stem Cell Therapies |
|---|---|---|---|---|
| Accelerated Bio | acceleratedbio.com | Carlsbad, CA | USA | Manufacturer of human Trophoblast Stem Cells (hTSCs) and hTSC-derived iPSCs for regenerative medicine. |
| Accellta | accellta.com | Haifa | Israel | Specializes in mass production of stem cells in 3D bioreactors |
| AIVITA Biomedical | aivitabiomedical.com | Irvine, CA | USA | Has a Phase II-approved immunotherapy that utilizes autologous dendritic cells loaded with irradiated tumor cells and a preclinical program developing 3D-retinal organoids for vision loss. |
| ALTuSTEM | altucell.net | Huntington, NY | USA | Cell therapies for the treatment of diabetes that utilize its Altucap Microencapsulation technology. |
| Anagenesis Biotechnologies | anagenesis-biotech.com | Boston, MA | USA | Preclinical‐stage stem cell company |
| Animal Cell Therapies | actcells.com | San Diego, CA | USA | Conducting a clinical trial evaluating intra-articular allogeneic umbilical-derived stem cells in canines with elbow osteoarthritis |
| apceth | www.apceth.com | Mountain View, CA | USA | Developing genetically engineered MSC (gmMSC) to target tumors and diseased tissue |
| Asterias Biotherapeutics | asteriasbiotherapeutics.com | Fremont, CA | USA | Pluripotent stem cells, cancer immunotherapies |
| Athersys | athersys.com | Cleveland, OH | USA | MultiStem®, an adult-derived “off-the-shelf” stem cell product platform |
| Betalin Therapeutics | betalintherapeutics.com | Ramat Gan | Israel | Betalin Therapeutics is developing an Engineered Micro Pancreas (EMP) to treat diabetes and recently submitted a pre-pre-IND application to the US FDA |
| BioCardia | biocardia.com | San Carlos, CA | USA | Clinical-stage therapeutics for cardiovascular diseases |
| BioRestorative Therapies | biorestorative.com | Jupiter, FL | USA | Stem cell company developing brtxDISC™ (Disc Implanted Stem Cells) & ThermoStem® |
| BlueRock Therapeutics | bluerocktx.com | New York, NY | USA | Allogeneic cell therapies with a focus on iPS cells |
| BrainStorm Cell Therapeutics | brainstorm-cell.com | Kiryat Aryeh, Israel | Israel | Autologous stem cell therapies for neurodegenerative disorders |
| CardioCell (Stemedica) | stemcardiocell.com | San Diego, CA | USA | Cardiovascular technology derived from allogeneic adult stem cells |
| Cell Cure Neurosciences (BioTime subsidiary) | cellcureneurosciences.com | Jerusalem | Israel | Cell therapies for retinal and neural degenerative diseases; Focus on hESC-derived RPE cells |
| Cellect Biosciences | cellect.co | Kfar Saba | Israel | ApoGraft™ technology for functional separation of stem cells |
| Cellenkos, Inc. | cellenkosinc.com | Houston, TX | USA | Developing cord blood-derived regulatory T-celll therapeutics for treating autoimmune diseases and inflammatory disorders |
| CellProthera | cellprothera.com | Mulhouse | France / USA | Use of blood peripheral stem cells for cardiac diseases |
| Celltex | celltexbank.com | Houston, TX | USA | Specializes in storing and expanding autologous adipose-derived MSC populations for use in regenerative medicine applications. |
| Cellular Biomedicine Group | cellbiomedgroup.com | Palo Alto, CA | USA | Immunotherapies for cancer and stem cell therapies for degenerative diseases |
| Cellular Dynamics (Fujifilm) | cellulardynamics.com | Madison, WI | USA | Largest global provider of research and clincal-grade iPS cells and their derivatives; Opsis Therapeutics is a subsidiary. |
| Celularity | celularity.com | Warren, NJ | USA | Developing therapies using cells and tissues from the placenta and umbilical cord |
| Celvive | celvive.com | New Brunswick, NJ | USA | Autologous adult stem cell therapies |
| Codiak Bio | codiakbio.com | Woburn, Massachusetts | USA | Therapeutic exosomes |
| Creative Medical Technology Holdings | creativemedicaltechnology.com | Phoenix, AZ | USA | Stem cell and exosome-based therapeutics |
| Cure Cell Neurosciences (Subsidiary of BioTime, Inc.) | cellcureneurosciences.com | Jerusalem, | Israel | ESC-derived therapies for retinal and neural degenerative diseases |
| Cynata Therapeutics | cynata.com | Armadale, VIC, | Australia | iPSC-derived MSCs; Cymerus platform technology |
| Cytori Therapeutics | cytori.com | Tokyo, | Japan | Medical devices that enable therapeutic use of adipose-derived stem and regenerative cells |
| DaVinci Biosciences | dvbiosciences.com | Yorba Linda, CA | USA | Stem cell therapies for spinal cord injury, cardiovascular disease, neurological disease, and more |
| DiscGenics | discgenics.com | Salt Lake City, UT | USA | Advanced spinal stem cell therapeutics; first product candidate, IDCT, is a homologous, allogeneic injectable cell therapy |
| Epibone | epibone.com | Brooklyn, NY | USA | Custom bone grafts grown from stem cells |
| ExCellThera | excellthera.ca | Montréal | Canada | Expands and genetically engineers hematopoietic stem cells as therapeutics with a focus on blood cancers and gene therapy (uses UM171 and a Fed-Batch culture system) |
| Exopharm | exopharm.com | Melbourne, VIC, | Australia | Manufacturing and applications of therapeutic exosomes from stem cells |
| Fate Therapeutics | fatetherapeutics.com | San Diego, CA | USA | Programmed cellular immunotherapeutics for cancer and immune disorders; Has an iPS cell product plaform |
| Fortuna Fix | fortunafix.com | Laval, QC, | Canada | Direct cell reprogramming for neural applications |
| FujiFilm Holdings | fujifilmholdings.com | Tokyo, | Japan | Diverse regenerative medicine company; Parent company of CDI |
| Gamida Cell | gamida-cell.com | Jerusalem, | Israel | HSCT therapies; Cord blood stem cell expansion |
| Gwo Xi Stem Cell Applied Technology Co., Ltd. (GWOXI) | gwoxi.com/tw | Zhubei City, Hsinchu County | Taiwan | Developing adult autologous adipose-derived stem cell (ADSC) therapies for liver cirrhosis, with lead candidates GXHPC1 and GXNPC1. |
| Healios KK | healios.co.jp/en/ | Tokyo | Japan | World pioneer in the development and manufacture of iPSC regenerative medicine products. Partnership with Athersys for the development of MultiStem®. |
| International Stem Cell | internationalstemcell.com | Carlsbad, CA | USA | Adult stem cell therapies utilizing human parthenogenetic stem cells (hpSC) |
| Invitrx Therapeutics | invitrx.com | Irvine, CA | USA | Harvesting and isolation of stem cells for therapeutic and cosmetic applications |
| Kadimastem | kadimastem.com | Nes-Ziona, | Israel | Stem cell-based therapeutics, primarily for diabetes and neurodegenerative disorders |
| Kiadis Pharma | kiadis.com | Amsterdam, | Netherlands | Developing ATIR101 and ATIR201 as cellular products for infusion. They consist of donor lymphocytes manufactured for each patient from a haploidentical stem cell donor. |
| Kimera Labs | kimeralabs.com | Miramar, FL | USA | A biotech company and CRO that develops umbilical cord and organ-based exosome products for research and therapeutic purposes. |
| Longeveron | longeveron.com | Miami, FL | USA | Developing human Allogeneic Mesenchymal Stem Cells (LMSCs) |
| Magenta Therapeutics | magentatx.com | Cambridge, MA | USA | Stem cell technologies to make stem cell transplantation safer |
| Medeor Therapeutics | medeortherapeutics.com | San Mateo, CA | USA | Cellular immunotherapy products for kidney transplant (MDR-10X) |
| Medipost | medi-post.com | Seongnam-si | South Korea | Relesed world’s first allogeneic stem cell drug (CARTISTEM®), an allogeneic cord blood-derived MSC therapy for knee cartilage defects CARTISTEM® |
| Mesoblast | mesoblast.com | Melbourne, VIC, | Australia | Stem cell therapies; Emphasis on MSC therapies |
| Minerva Bio | minervabio.com | Waltham, MA | USA | Cancer and stem cell therapeutics |
| Neuralstem | neuralstem.com | Germantown, MD | USA | Neural stem cell lines for potential transplantation therapies |
| Neurogeneration | neurogeneration.com | San Diego, CA | USA | Autologous stem cell treatments for Parkinson’s disease and other CNS disorders |
| Neurona Therapeutics | neuronatherapeutics.com | South SF, CA | USA | Transplantation of specialized neurons derived from stem cells to treat neurological diseases |
| Neuronascent | neuronascent.com | Clarksville, MD | USA | Utilization of neuronal progenitor cells for therapeutic applications |
| NextCell Pharma AB | hnextcellpharma.com | Stockholm | Sweden | Developing ProTrans™, consisting of stem cells for treatment of autoimmune and inflammatory diseases |
| Nohla Therapeutics | nohlatherapeutics.com | Seattle, WA | USA | Developing an ex vivo expanded cord blood product that will be a “universal donor” therapy |
| Orchard Therapeutics | orchard-tx.com | London | UK | Developing autologous stem cell treatments using ex-vivo gene therapy technology |
| ORIG3N | orig3n.com | Boston, MA | USA | World’s largest blood repository; Blood cell derived iPSCs |
| Osiris Therapeutics | www.osiristx.com | Columbia, MD | USA | Developed the first cellular bone allograft and first approved stem cell drug |
| OxStem | oxstem.co.uk | Cambridge, UK | UK | Cell programming therapies to treat degenerative diseases; Endogenous Cell Activation Therapy (ECAT) to activate stem and progenitor cells |
| Plureon | plureon.com | Winston-Salem, NC | USA | Pluripotent stem cells extracted from amniotic fluid and placenta |
| Pluristem Therapeutics | pluristem.com | Haifa, | Israel | Placental cell therapies |
| Promethera Biosciences | promethera.com | Mont-Saint-Guibert, | Belgium | Human liver-derived cell therapy technologies |
| Regeneus | regeneus.com.au | Pymble, NSW, | Australia | Allogeneic stem cell and secretions technologies |
| ReNeuron | reneuron.com | Bridgend, | UK | Stem cell therapies; therapeutic stem cell exosomes |
| RepliCel Life Sciences | replicel.com | Vancouver, BC | Canada | Autologous cell therapies with a focus on hair restoration |
| RichSource Stem Cells | richsourcestemcells.com | Boca Raton, FL | USA | Develops human tissue allograft combination products and membranes from birth tissues |
| SanBio Co Ltd | san-bio.com | Mountain View, CA | USA | Developing an allogeneic bone marrow derived MSC therapy (SB623, SB618, and SB308 cells) for ischemic stroke, brain injury, and more |
| Saneron CCEL Therapeutics (Affiliate of Cryo-Cell International, Inc) | saneron-ccel.com | Tampa, FL | USA | Developing U-CORD-CELL® (a cord blood stem cell product) and SERT-CELL (Sertoli cells) for neurological and cardiac applications |
| Semma Therapeutics | semma-tx.com | Cambridge, MA | USA | Generating stem cell-derived pancreatic beta cells to treat diabetes |
| Stem Cell Medicine, Ltd. | stemcell-medicine.com | Jerusalem, | Israel | Stem cell therapies |
| Stemedica Cell Technologies | stemedica.com | San Diego, CA | USA | Distributes adult allogeneic stem cell products for human trials |
| StemGenex | stemgenex.com | La Jolla, CA | USA | Stem cell therapy options for inflammatory and degenerative illnesses; Has 5 clinical studies registered with NIH |
| Steminent Biotherapeutics | steminent.com | Taipei City, | Taiwan | Adipose-derived stem cell therapies; Stemchymal® stem cell products |
| Stemline Therapeutics | stemline.com | New York, NY | USA | Therapies targeting cancer stem cells |
| Stempeutics | stempeutics.com | Bangalore, KA, | India | Developing stem cell therapeutics, including Stempeucel®, Stempeucare™ and Stempeutron™; Stempeucel® is 1st stem cell product approved by DCGI |
| Stratatech (a Mallinckrodt Pharmaceuticals Co.) | mallinckrodt.com | Madison, WI | USA | Stem cell company focused on therapeutic human skin substitutes |
| Taiga Biotechnologies | taigabiotech.com | Aurora, CO | USA | Stem cell therapeutics for the treatment of hematological malignancies |
| TaiwanBio | taiwan-bio-thera.com | Taipei City, | Taiwan | Human MSC based therapeutics utilizing a proprietary cell expansion technology; Lead products are Biochymal® and Chondrochymal® |
| Talisman Therapeutics (University of Cambridge spinout) | talisman-therapeutics.com | Cambridge, | UK | Developing novel human stem cell models of Alzheimer’s disease (AD) |
| Therapeutic Solutions International | therapeuticsolutionsint.com | Oceanside, California | USA | Undertaking clinical trials with JadiCell™ (umbilical cord derived MSCs) in COVID-19 ARDS and other applications |
| Tigenix | tigenix.com | Leuven, | Belgium | Stem cell therapies; Anti-inflammatory properties of stem cells |
| Tissue Regeneration Therapeutics Inc. | verypowerfulbiology.com | Toronto, Ontario | Canada | Stem Cell Therapies: Developing a patented human umbilical cord perivascular cell (HUCPVC) platform technology and its TXP cell therapy products |
| U.S. Stem Cell | us-stemcell.com | Sunrise, FL | USA | Stem cell treatments for patients with degenerative conditions; Has numerous US and EU clinical trials underway |
| Universal Cells | universalcells.com | Seattle, WA | USA | Creating “universal donor” stem cells by editing the genes required for immune recognition |
| Utah Cord Blood Bank | stemshot.com | Sandy, UT | USA | Hybrid public-private cord blood bank entering a RMAT for its tri-product consisting of cord blood, micronized amnion and micronized umbilical cord with Wharton’s Jelly |
| Vericel | vcel.com | Cambridge, MA | USA | Autologous cell-based therapies, including Carticel (autologous cultured chondrocytes) and Epicel (cultured epidermal autograft) |
| VetStem Biopharma | www.vet-stem.com | Poway, CA | USA | Concentrated autologous adipose-derived stem cells for veterinary applications |
| ViaCyte | viacyte.com | Athens, GA | USA | Using a ESC line to manufacture pancreatic endoderm cells (PEC-01) and developing an Encaptra cell delivery system to implant PEC-01 cells and other cell types |
| VistaStem Therapeutics (subsidiary of VistaGen Therapeutics) | vistagen.com | South SF, CA | USA | Has a human pluripotent stem cell technology (hPSC) platform; Signed sublicense agreement with BlueRock Therapeutics for use of its technologies to produce cardiac stem cells for heart disease |
| Xcelthera | xcelthera.com | San Diego, CA | USA | Developing PluriXcel human stem cell technology platforms and Xcel prototypes of human stem cell therapy products |
What other stem cell companies should be added? Add your suggestions in the comments below.