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Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) – Advances & Applications

MSC Market Report

Market Report, 351 Pages
December 2023

MSCs are multipotent cells that can differentiate into a variety of cell types, including but not limited to osteoblasts, chondrocytes, myocytes, and adipocytes. In addition to secreting factors that can stimulate tissue repair, MSCs can substantially alter their microenvironment, exerting effects that are both anti-inflammatory and anti-fibrotic. MSCs are advantageous over other cells types for a variety of reasons, including that they are immuno-evasive, making them an advantageous cell type for allogenic transplantation.

MSCs appear to be an exceptionally promising tool for cell therapy, because of their unusual advantages, which include availability, expandability, transplantability, and ethical implications. Interest in therapeutic applications of human MSCs arises from their diverse ability to impact human health, as well as their ability to migrate to sites of tissue injury/inflammation or tumor growth.

Naturally, a broad range of research products have been developed around MSCs and their differentiated cell types. Growing attention is also being given to manufacturing technologies to support commercial-scale production of MSCs. MSCs are also well-suited for use within the exponential growth fields of 3D printing and cultured meat production.

Numerous market competitors are exploring commercialization strategies for MSC-derived extracellular vesicles (EVs) and exosomes, because these extracellular “packages” represent a novel strategy for accessing the therapeutic effects of MSCs without the risks of administering whole cells to patients. Finally, gene editing of MSCs for overexpressing antitumor genes or therapeutic factors is broadening their application.

As a leading cell type being used within regenerative medicine, there is great potential for growth within the MSC market. Clinical trials involving MSC therapeutics surged in recent years, in part due to trials related to COVID-19. Current “hotspots” for MSC clinical trials include the U.S., E.U., China, the Middle East, and South Korea. While many early-stage MSC trials have demonstrated safety and efficacy, only a small number of MSC products have reached commercialization, indicating that the therapeutic market for MSCs remains early-stage.

Population aging and an increasing prevalence of chronic disease are driving interest in MSC-derived therapeutics. Meanwhile, demand for MSC-based research products is on the rise as well. Today, at least 113 different market competitors are developing various types of MSC-related products, services, therapies, and technologies.

Within this rapidly changing landscape, having a thorough understanding of the competition and their relative strengths and weaknesses is essential. Therefore, this global strategic report details the activities of leading MSC companies. It also presents detailed market size figures for the global MSC market, segmented by geography and business segment, and accompanied by future forecasts through 2030.

The main objectives of this report are to provide the reader with the following details:

With the competitive nature of this global market, you do not have the time to do the research. Claim this report to become immediately informed, without sacrificing hours of unnecessary research or missing critical opportunities.

About BioInformant

With an online readership of nearly one million viewers per year, BioInformant is a U.S. market research firm with 15 years of experience. As the first and only market research firm to specialize in the stem cell industry, BioInformant research has been cited by the Wall Street Journal, Xconomy, and Vogue Magazine. Founded in 2006 and headquartered in Washington, DC, BioInformant is strategically positioned to be near the National Institutes of Health (NIH), the U.S. FDA, the Maryland Biotech Corridor, and policy makers on Capitol Hill. In addition to leveraging an experienced team of analysts, BioInformant has unparalleled access to key opinion leaders (KOLs) from across the stem cell sector.

To analyze the rapidly evolving stem cell sector, BioInformant conducts interviews with prominent executives from across the field. BioInformant has interviewed representatives from Cynata Therapeutics (first company to bring an iPSC-derived MSC therapeutic product into a clinical trial), RoosterBio (specializes in manufacturing tens of billions of MSCs in suspension bioreactors), Celularity, Inc. (developing MSC therapeutics from the post-partum human placenta), Pluristem Therapeutics (commercializing placenta-derived mesenchymal-like adherent stromal cells in late-stage clinical trials), BioEden (leading company preserving MSCs derived from dental tissues), and Regenexx (world’s leading provider of MSC therapies for orthopedic applications).

The content within this report was compiled using a diverse range of sources, as described in this Research Methodology.

TABLE OF CONTENTS: Mesenchymal Stem Cells / Medicinal Signaling Cells (MSCs) – Advances & Applications


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